ReviewArrhythmia & electrophysiology review2018
Heart Rate Variability: An Old Metric with New Meaning in the Era of using mHealth Technologies for Health and Exercise Training Guidance. Part One: Physiology and Methods.
Review in Arrhythmia & electrophysiology review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06385197 (Improving the Effect of Dimethyl Fumarate and Diroximel Fumarate), which is not on this map. Cited by 69 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving the Effect of Dimethyl Fumarate and Diroximel Fumarate (DRF) for Patients With Multiple Sclerosis by Chronobiology
Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of amphetamines on blood pressure.The Cochrane database of systematic reviews · 2025Pooled it
- Can Reactivity of Heart Rate Variability Be a Potential Biomarker and Monitoring Tool to Promote Healthy Aging? A Systematic Review With Meta-Analyses.Frontiers in physiology · 2021Pooled it
- Melatonin Therapy Improves Cardiac Autonomic Modulation in Pinealectomized Patients.Frontiers in endocrinology · 2020Trial
- Validation of heart rate measurements from the polar verity sense during the submaximal Ekblom-Bak test in adult individuals with obesity.Journal of rehabilitation medicine · 2026Article
- A feasibility open-label clinical trial utilizing second-generation artificial intelligence based on the constrained-disorder principle in patients with Parkinson's disease.IBRO neuroscience reports · 2026Article
- Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity.Nature reviews. Cardiology · 2025Review
- Assessing Minority Stress and Physiological Response Through Ecological Momentary Assessment and Sensors: Protocol for a Feasibility and Acceptability of the Stress and Heart Pilot Study.JMIR formative research · 2025Article
- Exploring associations between sleep duration and performance as well as heart rate variability in elite esports athletes.Scientific reports · 2025Article
- Heart Rate Variability in Adolescents with Autistic Spectrum Disorder Practicing a Virtual Reality Using Two Different Interaction Devices (Concrete and Abstract): A Prospective Randomized Crossover Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- Validity of Heart Rate Variability Measured with Apple Watch Series 6 Compared to Laboratory Measures.Sensors (Basel, Switzerland) · 2025Article
- Heart Rate Variability Subsequent to Auriculotherapy Among Individuals Afflicted by Major Burn Scars.Annals of plastic surgery · 2025Article
- Effective engagement in computerized cognitive training for older adults.Ageing research reviews · 2025Review
- Test-Retest Reliability and Concurrent Validity of Photoplethysmography Finger Sensor to Collect Measures of Heart Rate Variability.Sports (Basel, Switzerland) · 2025Article
- Detailed evaluation of sleep apnea using heart rate variability: a machine learning and statistical method using ECG data.Frontiers in neurology · 2025Article
- Genetic Algorithms for Feature Selection in the Classification of COVID-19 Patients.Bioengineering (Basel, Switzerland) · 2024Article
- Review
- A Feasibility Open-Labeled Clinical Trial Using a Second-Generation Artificial-Intelligence-Based Therapeutic Regimen in Patients with Gaucher Disease Treated with Enzyme Replacement Therapy.Journal of clinical medicine · 2024Article
- Stress-Induced Autonomic Dysfunction is Associated With Mental Stress-Induced Myocardial Ischemia in Patients With Coronary Artery Disease.Circulation. Cardiovascular imaging · 2024Article
- Heart Rate Variability Applications in Strength and Conditioning: A Narrative Review.Journal of functional morphology and kinesiology · 2024Review
- Remote Short Sessions of Heart Rate Variability Biofeedback Monitored With Wearable Technology: Open-Label Prospective Feasibility Study.JMIR mental health · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The autonomic nervous system plays a major role in optimising function of the cardiovascular (CV) system, which in turn has important implications for CV health. Heart rate variability (HRV) is a measurable reflection of this balance between sympathetic and parasympathetic tone and has been used as a marker for cardiac status and predicting CV outcomes. Recently, the availability of commercially available heart rate (HR) monitoring systems has had important CV health implications and permits ambulatory CV monitoring on a scale not achievable with traditional cardiac diagnostics. The focus of the first part of this two-part review is to summarise the physiology of HRV and to describe available technologies for HRV monitoring. Part two will present HRV measures for assessing CV prognosis and athletic training.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.