Evidence map›Paper›PMID 30416696›Full record

ArticleMediterranean journal of hematology and infectious diseases2018

Jadenu

Mohamed A Yassin, Ashraf T Soliman, Vincenzo De Sanctis, Radwa M Hussein, Randa Al-Okka, Nancy Kassem, Rula Ghasoub, Ahmed Basha, Abdulqadir J Nashwan, Ahmad M Adel

Abstract read
In one paragraph

Article in Mediterranean journal of hematology and infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Review
  4. Iron chelators: as therapeutic agents in diseases.Annals of medicine and surgery (2012) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohamed A YassinHematology Section, National Center for Cancer Care and Research, Hamad Medical Corporation, (HMC), Doha, Qatar.
Ashraf T SolimanDepartments of Pediatrics, University of Alexandria, Alexandria, Egypt.
Vincenzo De SanctisPediatric and Adolescent Outpatient Clinic, Quisisana Hospital, Ferrara, Italy.
Radwa M HusseinPharmacists, Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.
Randa Al-OkkaPharmacists, Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.
Nancy KassemPharmacists, Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.
Rula GhasoubPharmacists, Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.
Ahmed BashaPharmacists, Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.
Abdulqadir J NashwanNurse Research Scientist, Cancer Clinical Trials Unit, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.
Ahmad M AdelPharmacists, Department of Pharmacy, National Center for Cancer Care and Research, Hamad Medical Corporation (HMC), Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDue to the chronic nature of chelation therapy and the adverse consequences of iron overload, patient adherence to therapy is an important issue. Jadenu PATIENTS AND

methodsTwelve selected adult patients BMT (mean age: 29 years; range:15-34 years) were enrolled in the study. All patients were on monthly regular red cell transfusion therapy to keep their pre-transfusional hemoglobin (Hb) level not less than 9 g/dL. They were on Exjade

resultsApart from some minor gastrointestinal complaints reported in 3 BMT patients that did not require discontinuation of therapy, other side effects were not registered during the treatment. Subjectively, patients reported an improvement in the palatability of Jadenu

conclusionsOur study shows that short-term treatment with Jadenu

Indexed as

Adverse eventsChelation therapyDeferasiroxLiver iron concentrationPatient’s satisfactionSerum ferritinThalassemia major

Identifiers

PMID30416696
PMCPMC6223544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.