Evidence map›Paper›PMID 30416679›Full record

ArticleOncotarget2018

Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8.

Chiara Russo, Chiara Giannotti, Alessio Signori, Michele Cea, Roberto Murialdo, Alberto Ballestrero, Stefano Scabini, Emanuele Romairone, Patrizio Odetti, Alessio Nencioni and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Guideline
  2. Frailty screening in dermato-oncology practice: a modified Delphi study and a systematic review of the literature.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
    Pooled it
  3. Article
  4. Cardio-Oncology Challenges in Elderly Patients.Journal of clinical medicine · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. A Two-Step Frailty Assessment Strategy in Older Patients With Solid Tumors: A Decision Curve Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Chiara Russo *Department of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Chiara Giannotti *Department of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Alessio SignoriDISSAL, Section of Biostatistics, Department of Health Sciences, University of Genova, Genoa, Italy.
Michele CeaDepartment of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Roberto MurialdoDepartment of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Alberto BallestreroDepartment of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Stefano ScabiniHospital Policlinic San Martino, Oncological Surgery and Implantable Systems, Genoa, Italy.
Emanuele RomaironeHospital Policlinic San Martino, Oncological Surgery and Implantable Systems, Genoa, Italy.
Patrizio OdettiDepartment of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Alessio NencioniDepartment of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
Fiammetta MonacelliDepartment of Internal Medicine and Medical Specialties (DIMI), Section of Geriatrics, Genoa, Italy.
University of Genoa · ITOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesComprehensive Geriatric Assessment (CGA), the gold standard for detecting frailty in elderly cancer patients, is time-consuming and hard to apply in routine clinical practice. Here we compared the performance of two screening tools for frailty, G8 and SAOP2 for their accuracy in identifying vulnerable patients. MATERIAL AND

methodsWe tested G8 and SAOP2 in 282 patients aged 65 or older with a diagnosis of solid cancer and candidate to undergo surgical, medical and/or radiotherapy treatment. CGA, including functional and cognitive status, depression, nutrition, comorbidity, social status and quality of life was used as reference. ROC curves were used to compare two screening tools.

resultsMean patient age was 79 years and 54% were female. Colorectal and breast cancer were the most common types cancer (49% and 24%). Impaired CGA, G8, and SAOP2 were found in 62%, 89%, and 94% of the patients, respectively. SAOP2 had a better sensitivity (AUC 0.85, p<0.032) than G8 (AUC 0.79), with higher performance in breast cancer patients (AUC 0.93) and in patients aged 70-80 years (AUC 0.87).

conclusionsG8 and SAOP2 both showed good screening capacity for frailty in the cancer patient population we examined with SAOP2 showing a slightly better performance than G8.

Indexed as

agingcancerfrailtygeriatric assessmentscreening tool

Identifiers

PMID30416679
PMCPMC6205549
OpenAlexW2896580584

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.