Evidence map›Paper›PMID 30416659›Full record

ArticleAmerican journal of translational research2018

Alterations of fecal bacterial communities in patients with lung cancer.

Wei-Quan Zhang, Shu-Kang Zhao, Jun-Wen Luo, Xiao-Peng Dong, Ying-Tao Hao, Hui Li, Lei Shan, Yong Zhou, Hu-Bo Shi, Zai-Yun Zhang and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. [Fecal Microbiota Transplantation: A Promising Avenue for Lung Cancer Therapy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Pooled it
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  4. Review
  5. Probiotics Cancer Interaction, Prevention, and Therapy.Immunity, inflammation and disease · 2026
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Wei-Quan ZhangDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Shu-Kang ZhaoDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Jun-Wen LuoDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Xiao-Peng DongDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Ying-Tao HaoDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Hui LiDepartment of Pathology, The Second Hospital of Shandong University Shandong, P. R. China.
Lei ShanDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Yong ZhouCancer Center, The Second Hospital of Shandong University Shandong, P. R. China.
Hu-Bo ShiDepartment of Thoracic Surgery, Shandong Provincial Chest Hospital Jinan 250000, Shandong, P. R. China.
Zai-Yun ZhangCancer Center, The Second Hospital of Shandong University Shandong, P. R. China.
Chuan-Liang PengDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Xiao-Gang ZhaoDepartment of Thoracic Surgery, The Second Hospital of Shandong University Shandong, P. R. China.
Second Hospital of Shandong University · CNShandong University · CNShandong Chest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence suggests the microbiome may affect a number of diseases, including lung cancer. However, the direct relationship between gut bacteria and lung cancer remains uncharacterized. In this study, we directly sequenced the hypervariable V1-V2 regions of the 16S rRNA gene in fecal samples from patients with lung cancer and healthy volunteers. Unweighted principal coordinate analysis (PCoA) revealed a clear difference in the bacterial community membership between the lung cancer group and the healthy control group. The lung cancer group had remarkably higher levels of

Indexed as

16S rRNA gene sequencingcarcinogenesisgut bacteriaLung cancermicrobial dysbiosis

Identifiers

PMID30416659
PMCPMC6220220
OpenAlexW2991280650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.