ReviewAdolescent medicine: state of the art reviews2017
GENETIC AND EPIGENETIC CAUSES OF OBESITY.
Review in Adolescent medicine: state of the art reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 4 syntheses or guidelines pooled it, 224 citations in OpenAlex.
- Socioeconomic position, genetic susceptibility, and epigenetic profiles in obesity across the life course: a systematic review.International journal of obesity (2005) · 2026Pooled it
- Uncovering the Causal Link Between Obesity-Associated Genes and Multiple Sclerosis: A Systematic Literature Review.Brain and behavior · 2025Pooled it
- Impact of Food-Based Weight Loss Interventions on Gut Microbiome in Individuals with Obesity: A Systematic Review.Nutrients · 2022Pooled it
- Factors associated with weight regain post-bariatric surgery: a systematic review.Surgical endoscopy · 2021Pooled it
- Improved health-related quality of life with tirzepatide versus semaglutide in adults with obesity or overweight from the SURMOUNT-5 trial.Diabetes, obesity & metabolism · 2026Trial
- Effect of Diet before Bariatric Surgery on Ghrelin Level through DNA Methylation.Annals of nutrition & metabolism · 2024Trial
- Integrated Analysis of microRNA Expression, Lymphocyte Counts, and Metabolic Parameters in Obese Individuals.International journal of molecular sciences · 2026Article
- The Influence of Genetic Background and Housing Conditions on Spontaneous Obesity in Captive-Bred Rhesus Monkeys (Macaca mulatta).Journal of medical primatology · 2026Article
- Mapping weight stigma in food-based dietary guidelines across thirteen countries in Latin America and the Caribbean: a qualitative analysis.Lancet regional health. Americas · 2026Article
- Management of Childhood Obesity.International journal of molecular sciences · 2026Review
- Functional characterisation of obesity-associated MRAP2 variants on MC4R and GHSR signalling.Human molecular genetics · 2026Article
- Reexamining Fat: Exploring Diversity, Plasticity, Development, Functional Implication, and Therapeutic Options.International journal of molecular sciences · 2026Review
- Multi-Omics Analysis of Morbid Obesity Using a Patented Unsupervised Machine Learning Platform: Genomic, Biochemical, and Glycan Insights.International journal of molecular sciences · 2026Article
- In Vivo Gastric Expression of FTO and MC4R in Sleeve Gastrectomy Patients: Diagnostic Utility Without Predictive Value for Weight Loss.Obesity surgery · 2026Article
- The 'obesity paradox' in patients undergoing transcatheter aortic valve implantation. A specialized narrative review.American heart journal plus : cardiology research and practice · 2026Review
- Influences of genetic factors for educational attainment and cognitive functions on current dietary consumption.iScience · 2025Article
- A Microarray, Validation, and Gene-Enrichment Approach for Assessing Differentially Expressed Circulating miRNAs in Obese and Lean Heart Failure Patients: A Case-Control Study.International journal of molecular sciences · 2025Article
- Obesity as a Multifactorial Chronic Disease: Molecular Mechanisms, Systemic Impact, and Emerging Digital Interventions.Current issues in molecular biology · 2025Review
- Adipose-specific HuR deletion protects against high-fat diet-induced obesity in mice through upregulating Ucp1 expression.Lipids in health and disease · 2025Article
- The effects of high fat diet consumption on morphine-induced constipation.Behavioural pharmacology · 2025Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Obesity is a complex, heritable trait influenced by the interplay of genetics, epigenetics, metagenomics and the environment. With the increasing access to high precision diagnostic tools for genetic investigations, numerous genes influencing the phenotype have been identified, especially in early onset severe obesity. This review summarizes the current knowledge on the known genetic causes of obesity and the available therapeutic options. Furthermore, we discuss the role and potential mechanism of epigenetic changes that may be involved as mediators of the environmental influences and that may provide future opportunities for intervention.
Indexed as
Identifiers
30416642PMC6226269W2991550491What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.