ArticleLighting research & technology (London, England : 2001)2018
Non-visual effects of light: how to use light to promote circadian entrainment and elicit alertness.
Article in Lighting research & technology (London, England : 2001), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05535790 (PAX), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PAX: A Randomized Single-blind Controlled Trial of the Effect of Circadian Light on Hospitalized Persons With Dementia and Older Adults With Cognitive Impairments
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ocular light and optical radiation exposure as a modifiable environmental determinant of health: expert consensus on research gaps and priorities.BMC medicine · 2026Guideline
- A systematic review and meta-analysis on light therapy for sleep disorders in shift workers.Scientific reports · 2025Pooled it
- Light Exposure as a Modifiable Determinant of Mental Health.Current psychiatry reports · 2026Review
- Disentangling the functional roles of pre-stimulus oscillations in crossmodal associative memory formation via sensory entrainment.Scientific reports · 2026Article
- Comparative Effects of Red and Blue LED Light on Melatonin Levels During Three-Hour Exposure in Healthy Adults.Life (Basel, Switzerland) · 2025Article
- Analyzing display photometric features through time-dependent dynamics of accommodative responses and ocular imaging quality.Scientific reports · 2025Article
- Towards an evidence-based integrative lighting score: a proposed multi-level approach.Annals of medicine · 2024Review
- Photophobia is associated with lower sleep quality in individuals with migraine: results from the American Registry for Migraine Research (ARMR).The journal of headache and pain · 2024Observational
- Effects of Post-awakening Light Exposure on Heart Rate Variability in Healthy Male Individuals.Applied psychophysiology and biofeedback · 2023Article
- Cellular and molecular alterations in neurons and glial cells in inherited retinal degeneration.Frontiers in neuroanatomy · 2022Review
- Light Therapy for Cancer-Related Fatigue in (Non-)Hodgkin Lymphoma Survivors: Results of a Randomized Controlled Trial.Cancers · 2021Article
- Access to Daylight at Home Improves Circadian Alignment, Sleep, and Mental Health in Healthy Adults: A Crossover Study.International journal of environmental research and public health · 2021Article
- Lighting and Alzheimer's Disease and Related Dementias: Spotlight on Sleep and Depression.Lighting research & technology (London, England : 2001) · 2021Article
- The Effect of Fluorescent Light on Anxiety Patients.Cureus · 2021Article
- Effects of Daytime Electric Light Exposure on Human Alertness and Higher Cognitive Functions: A Systematic Review.Frontiers in psychology · 2021Review
- Does Bright Light Counteract the Post-lunch Dip in Subjective States and Cognitive Performance Among Undergraduate Students?Frontiers in public health · 2021Article
- Intermittent Light Exposures in Humans: A Case for Dual Entrainment in the Treatment of Alzheimer's Disease.Frontiers in neurology · 2021Review
- Temporal Dynamics of Subjective and Objective Alertness During Exposure to Bright Light in the Afternoon for 5 h.Frontiers in physiology · 2021Article
- Human-Centric Lighting: Foundational Considerations and a Five-Step Design Process.Frontiers in neurology · 2021Review
- Blue-Enriched White Light Improves Performance but Not Subjective Alertness and Circadian Adaptation During Three Consecutive Simulated Night Shifts.Frontiers in psychology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
In addition to stimulating the visual system, light incident on the retina stimulates other biological functions, also referred to as non-visual responses. Among the most notable biological functions are human circadian rhythms, which are bodily rhythms that, in constant darkness, oscillate with a period close to, but typically slightly longer than 24 hours. Twenty-four-hour light-dark patterns incident on the retina are the major synchronizer of circadian rhythms to the local time on Earth. Entrainment of circadian rhythms has been implicated in health and well-being. Light can also elicit an acute alerting effect on people, similar to a "cup of coffee." This review summarizes the literature on how light affects entrainment and alertness and how it can be used to achieve these aims.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.