Evidence map›Paper›PMID 30415994›Full record

ArticleNeuron2018

Visual Control of Walking Speed in Drosophila.

Matthew S Creamer, Omer Mano, Damon A Clark

Abstract readVideo-Audio Media
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Afterimages drive a shared visual motion-reversal illusion inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025
    Review
  5. The fruit fly,Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Optimization in Visual Motion Estimation.Annual review of vision science · 2024
    Review
  11. Broken time reversal symmetry in visual motion detection.bioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. TheMolecules and cells · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthew S CreamerInterdepartmental Neuroscience Program, Yale University, New Haven, CT 06511, USA.
Omer ManoDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Damon A ClarkInterdepartmental Neuroscience Program, Yale University, New Haven, CT 06511, USA; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA; Department of Physics, Yale University, New Haven, CT 06511, USA. Electronic address: damon.clark@yale.edu.

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007499 · NIGMS · YALE UNIVERSITY · PI CARLSON, JOHN R, REINKE, VALERIE J · 1985 to 2022
$13.9M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Interdepartmental Neuroscience Program (INP)T32NS041228 · NINDS · YALE UNIVERSITY · PI Charles A Greer, Marina R Picciotto · 2001 to 2026
$12.0M
Yale Core Grant for Vision ResearchP30EY026878 · NEI · YALE UNIVERSITY · PI In-Jung Kim · 2016 to 2026
$7.1M
Integrating visual counterevidence to detect self-motion in a small visual circuitR01EY026555 · NEI · YALE UNIVERSITY · PI CLARK, DAMON ALISTAIR · 2016 to 2025
$4.0M
NEI NIH HHS P30 EY026878NEI NIH HHS R01 EY026555NIGMS NIH HHS T32 GM007499NIH HHS P40 OD018537NINDS NIH HHS T32 NS041228
6 · The paper itself

Abstract

An animal's self-motion generates optic flow across its retina, and it can use this visual signal to regulate its orientation and speed through the world. While orientation control has been studied extensively in Drosophila and other insects, much less is known about the visual cues and circuits that regulate translational speed. Here, we show that flies regulate walking speed with an algorithm that is tuned to the speed of visual motion, causing them to slow when visual objects are nearby. This regulation does not depend strongly on the spatial structure or the direction of visual stimuli, making it algorithmically distinct from the classic computation that controls orientation. Despite the different algorithms, the visual circuits that regulate walking speed overlap with those that regulate orientation. Taken together, our findings suggest that walking speed is controlled by a hierarchical computation that combines multiple motion detectors with distinct tunings. VIDEO ABSTRACT.

Indexed as

AlgorithmsAnimalsCuesDrosophilaMotionMotion PerceptionNeuronsOptic FlowOrientationPhotic StimulationSpatial NavigationWalking Speedbehavioral algorithmsDrosophilanavigationneural circuitsoptomotor behaviorspeed tuningtemporal frequency tuningvisual motion detectionvisual processingwalking speed

Identifiers

PMID30415994
PMCPMC6405217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.