Evidence map›Paper›PMID 30415806›Full record

ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2018

Military-related risk factors for dementia.

Heather M Snyder, Roxana O Carare, Steven T DeKosky, Mony J de Leon, Derek Dykxhoorn, Li Gan, Raquel Gardner, Sidney R Hinds, Michael Jaffee, Bruce T Lamb and 11 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Association between military service and Alzheimer's disease neuropathology at autopsy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Heather M SnyderMedical & Scientific Relations, Alzheimer's Association, Chicago, IL, USA. Electronic address: hsnyder@alz.org.
Roxana O CarareClinical Neuroanatomy, Equality and Diversity Lead, University of Southampton, Southampton, United Kingdom.
Steven T DeKoskyDepartment of Neurology and Neuroscience, University of Florida, Gainesville, FL, USA.
Mony J de LeonDepartment of Psychiatry, New York University Medical Center, New York City, NY, USA.
Derek DykxhoornDepartment of Microbiology and Immunology, Miami University, Miami, FL, USA.
Li GanGladstone Institute, University of California, San Francisco, San Francisco, CA, USA.
Raquel GardnerDepartment of Psychiatry, Neurology & Epidemiology, University of California, San Francisco, San Francisco, CA, USA.
Sidney R HindsBlast Injury Research Program Coordinating Office, United States Army Medical Research and Material Command, Frederick, MD, USA.
Michael JaffeeDepartment of Neurology and Neuroscience, University of Florida, Gainesville, FL, USA.
Bruce T LambStark Neurosciences Research Institute, Indiana University, Indianapolis, IN, USA.
Susan LandauHelen Willis Neuroscience Institute, University of California, Berkley, Berkley, CA, USA.
Geoff ManleyDepartment of Psychiatry, Neurology & Epidemiology, University of California, San Francisco, San Francisco, CA, USA.
Ann McKeeDepartment of Neurology and Pathology, Boston University, Boston, MA, USA.
Daniel PerlDepartment of Pathology, Uniformed Services University, Bethesda, MD, USA.
Julie A SchneiderNeurology Department, Rush University Medical Center, Chicago, IL, USA.
Michael WeinerDepartment of Radiology, University of California San Francisco, San Francisco, CA, USA.
Cheryl WellingtonDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
Kristine YaffeDepartment of Psychiatry, Neurology & Epidemiology, University of California, San Francisco, San Francisco, CA, USA.
Lisa BainIndependent Science Writer, Philadelphia, PA, USA.
Anthony M PacificoCongressionally Directed Medical Research Programs, Frederick, MD, USA.
Maria C CarrilloMedical & Scientific Relations, Alzheimer's Association, Chicago, IL, USA.

Funding

Neuropathology CoreP30AG013846 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOWALL, NEIL W. · 1996 to 2020
$29.1M
University of Florida - Mt. Sinai Medical Center AD Research CenterP50AG047266 · NIA · UNIVERSITY OF FLORIDA · PI FEBO, MARCELO · 2015 to 2019
$7.3M
PREDICTORS OF COGNITIVE DECLINE IN NORMAL AGINGR01AG012101 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DE LEON, MONY J., RUSINEK, HENRY · 1993 to 2015
$6.7M
CLINICAL CORRELATES OF LONGITUDINAL PET CHANGES IN ADR01AG013616 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DE LEON, MONY J. · 1995 to 2013
$6.2M
Biomarkers in Early Alzheimer's Disease (AD).R01AG022374 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DE LEON, MONY J., RUSINEK, HENRY · 2004 to 2015
$5.2M
The Contribution of Age-Related Taupahtoies to Alzheimer's Disease-SupplementR01AG062348 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CRARY, JOHN FONDA, DICKSON, DENNIS WILLIAM · 2018 to 2022
$4.5M
PET Measures of CSF Clearance in Preclinical Alzheimer's DiseaseRF1AG057570 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE LEON, MONY J. · 2017 to 2017
$4.1M
Tau Pathology in CTE vs. Alzheimer's Disease: Microvasculopathy and NeuroinflammationRF1AG057902 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MCKEE, ANN C. · 2017 to 2017
$4.1M
Tau acetylation in Alzheimer's diseaseR01AG054214 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI GAN, LI · 2017 to 2021
$3.3M
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical TrajectoriesK23NS095755 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARDNER, RAQUEL C. · 2015 to 2019
$872k
CSF Clearance with 11C-Butanol PET Predicts Amyloid DepositionR56AG058913 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE LEON, MONY J., RUSINEK, HENRY · 2018 to 2018
$861k
NIA NIH HHS P30 AG013846NIA NIH HHS P50 AG047266NIA NIH HHS R01 AG012101NIA NIH HHS R01 AG013616NIA NIH HHS R01 AG022374NIA NIH HHS R01 AG054214NIA NIH HHS R01 AG062348NIA NIH HHS R56 AG058913NIA NIH HHS RF1 AG057570NIA NIH HHS RF1 AG057902NINDS NIH HHS K23 NS095755
6 · The paper itself

Abstract

introductionIn recent years, there has been growing discussion to better understand the pathophysiological mechanisms of traumatic brain injury and post-traumatic stress disorder and how they may be linked to an increased risk of neurodegenerative diseases including Alzheimer's disease in veterans.

methodsBuilding on that discussion, and subsequent to a special issue of Alzheimer's & Dementia published in June 2014, which focused on military risk factors, the Alzheimer's Association convened a continued discussion of the scientific community on December 1, 2016.

resultsDuring this meeting, participants presented and evaluated progress made since 2012 and identified outstanding knowledge gaps regarding factors that may impact veterans' risk for later life dementia. DISCUSSION: The following is a summary of the invited presentations and moderated discussions of both the review of scientific understanding and identification of gaps to inform further investigations.

Indexed as

Military PersonnelVeteransAnimalsBrain Injuries, TraumaticCongresses as TopicDementiaHumansRisk Factors

Identifiers

PMID30415806
PMCPMC6281800

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.