ReviewJournal of medical case reports2018
Congenital intrahepatic portocaval shunts and hypoglycemia due to secondary hyperinsulinism: a case report and review of the literature.
Review in Journal of medical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Prenatal sonographic characteristics and postnatal outcomes of congenital portosystemic shunt diagnosed during the fetal period: a systematic review.Orphanet journal of rare diseases · 2025Pooled it
- A congenital portosystemic shunt in the neonatal period: case report and literature review.Frontiers in pediatrics · 2026Article
- Etiology and treatment of recurrent consciousness disorders following hepatobiliary surgery: Insights from a portosystemic shunt case study.The Journal of international medical research · 2025Article
- Reactive hypoglycemia owing to an intrahepatic congenital portosystemic shunt in an older patient.Diabetology international · 2023Article
- Abnormal glucose homeostasis and fasting intolerance in patients with congenital porto-systemic shunts.Frontiers in endocrinology · 2023Review
- Case Report: Clinical Features of Congenital Portosystemic Shunts in the Neonatal Period.Frontiers in pediatrics · 2021Article
- Abernethy syndrome in Slovenian children: Five case reports and review of literature.World journal of gastroenterology · 2020Review
- Congenital intrahepatic portosystemic venous shunt embolization: A two-case experience.Clinical case reports · 2020Article
- The physiological implications of absent ductus venosus during fetal and post-natal life.Annals of pediatric cardiologyArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCongenital portosystemic shunts present with various associated complications, such as other congenital malformations, hyperammonemia, or hepatopulmonary syndrome. Few cases of associated hypoglycemia have been reported so far and our case, to the best of our knowledge, describes the most severe extent of hypoglycemia. CASE PRESENTATION: We describe the case of a newborn Arab boy with two intrahepatic portosystemic shunts, resulting in severe and persistent hypoglycemia, due to which one of the shunts was closed by interventional radiology whereas the other shunt had already closed spontaneously.
conclusionsBecause he showed elevated levels for insulin and prolonged high insulin levels in an oral glucose tolerance test, our case supports the theory that portocaval shunts cause a reduced hepatic insulin reduction due to the high blood volume bypassing the liver. This case provides further insights into glucose regulation mechanisms of the liver and we suggest a consistent screening for hypoglycemia in patients with congenital portosystemic shunts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.