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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study.

Rodolfo Castro, Raquel B De Boni, Paula M Luz, Luciane Velasque, Livia V Lopes, Antonieta Medina-Lara, Sandra W Cardoso, Marilia S De Oliveira, Ruth K Friedman, Beatriz Grinsztejn and 1 more

Abstract read
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. An international compendium of health state utilities in people with HIV: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. The associations between HIV stigma and mental health symptoms, life satisfaction, and quality of life among Black sexual minority men with HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  7. Article
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  9. HIV and Substance Use in Latin America: A Scoping Review.International journal of environmental research and public health · 2022
    Article
  10. Article
  11. Article
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  13. Sexualized Drug Use and Chemsex: Their Association with Sexual Health Among Men who have Sex with Men Living in Greece.International journal of sexual health : official journal of the World Association for Sexual Health · 2022
    Article
  14. Article
  15. Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  16. Health-related quality of life of type 2 diabetes patients hospitalized for a diabetes-related complication.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  17. Development of algorithms to estimate EQ-5D and derive health utilities from WHOQOL-HIV Bref: a mapping study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rodolfo CastroInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil. rodolfoalcastro@gmail.com.ORCID http://orcid.org/0000-0002-0701-2528
Raquel B De BoniInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Paula M LuzInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Luciane VelasqueUniversidade Federal do Estado do Rio de Janeiro, Departamento de Matemática e Estatística, Avenida Pasteur, 458, Urca, Rio de Janeiro, RJ, 22290-240, Brazil.
Livia V LopesInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Antonieta Medina-LaraUniversity of Exeter, Health Economics Group, South Cloisters, St Luke's Campus, Heavitree Road, Exeter, Devon, EX1 2LU, UK.
Sandra W CardosoInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Marilia S De OliveiraInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Ruth K FriedmanInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Beatriz GrinsztejnInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.
Valdiléa G VelosoInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil, Manguinhos, Rio de Janeiro, 4365, Rio de Janeiro, RJ, 21040-360, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 476024/2013-7Conselho Nacional de Desenvolvimento Científico e Tecnológico 476333/2013-0Conselho Nacional de Desenvolvimento Científico e Tecnológico Programa Institucional de Bolsas de Iniciação CientíficaFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/170.021/2015
6 · The paper itself

Abstract

purposeTo assess health-related quality of life (HRQoL) and its associated factors among people living with HIV/AIDS (PLWHA) in Rio de Janeiro, Brazil.

methodsA cross-sectional study including PLWHA receiving usual HIV-care at Instituto Nacional de Infectologia Evandro Chagas (INI/Fiocruz) was conducted between 2014 and 2016 in Rio de Janeiro, Brazil. The EQ-5D-3L assessed HRQoL; PHQ-2 and ASSIST were used for screening depression and substance use, respectively. Clinical variables were obtained from the INI/Fiocruz cohort database, and structured questions evaluated intimate partner violence, sexual abstinence and relationship status. Data were analysed using multivariable Tobit regression model.

resultsA total of 1480 PLWHA were included: 64.7% were male at birth (38.4% men who have sex with men [MSM], 24.3% heterosexual men and 2% transgender women [TGW]); median age was 43.1 years, and 95.8% were receiving antiretroviral therapy. The median EQ-5D-3L utility score was 0.801. Results showed that the following factors: MSM and women; older age; lower educational level; no engagement in a relationship; depression screening positive; polysubstance use; and, detectable viral load were independently associated with worse HRQoL.

conclusionsPLWHA under care at INI/Fiocruz presented good HRQoL. Polysubstance use, depression and lower educational level were among the factors negatively associated with HRQoL. This was the first time that the EQ-5D-3L utility scores were calculated for a considerable number of PLWHA in Brazil, which is a fundamental piece of information for future cost-effectiveness analysis.

Indexed as

AdultBrazilCross-Sectional StudiesFemaleHIVHIV InfectionsHumansMaleQuality of LifeAge factorsDepressionEducational statusGenderQuality of lifeSubstance abuseViral load, HIV

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.