ReviewDigestive diseases and sciences2019
Malignant Transformation of Ectopic Pancreas.
Review in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04913077 (Prospective One-armed Observational Study of Full-thickness Resection of Small Hypoechoic Submucosal Gastric Tumors), which is not on this map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective One-armed Observational Study of Full-thickness Resection of Small Hypoechoic Submucosal Gastric Tumors (≤2 cm)
Who cites it
43 citing papers in PubMed, 63 citations in OpenAlex.
- Heterotopic pancreas as a rare lead point of ileal intussusception mimicking acute appendicitis in a child: a case report and review of the literature.International journal of surgery case reports · 2026Article
- Pancreatic cancer mimicking ectopic pancreas origin: a rare case after neonatal pyloromyotomy.Clinical journal of gastroenterology · 2026Article
- Multidisciplinary Treatment for Advanced Pancreatic Adenocarcinoma Arising from Esophageal Heterotopic Pancreas in a Young Adult: A Case Report.Surgical case reports · 2026Article
- Pancreatic Choristoma of the Spleen, a Rare Incidental Finding: A Case Report.International medical case reports journal · 2026Article
- Ectopic Pancreatic Adenocarcinoma Arising in the Mesentery of the Jejunum: A Case Report.Surgical case reports · 2026Article
- Primary adenocarcinoma from a gastric heterotopic pancreas: A case report.World journal of gastrointestinal endoscopy · 2025Article
- A case of jejunal cancer arising from ectopic pancreas.Clinical journal of gastroenterology · 2025Article
- Heterogeneity of pancreatic neoplasms arising in pancreatic heterotopia: a single institution review.Virchows Archiv : an international journal of pathology · 2025Article
- Various Phenotypes of Ectopic Pancreatic Tissue in Children: Case Series and Literature Review.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Review
- Ectopic Pancreatic Tissue in the Gallbladder Following Laparoscopic Cholecystectomy: A Rare Case.Cureus · 2025Article
- Congenital duodenal diaphragm with heterotopic pancreas: a case report and literature review.Frontiers in pediatrics · 2025Article
- Gastric ectopic pancreatic ductal adenocarcinoma coexisted with endometriosis mimick advanced disease: a case report and literature review.Frontiers in oncology · 2025Article
- Mixed Pancreatobiliary Ductal Adenocarcinoma and Squamous Cell Carcinoma Arising from an Ectopic Pancreas in a Gastric Duplication Cyst-A Rare Double Diagnosis.Diagnostics (Basel, Switzerland) · 2024Article
- INTESTINAL OBSTRUCTION AS A RESULT OF PANCREATIC ECTOPY IN JEJUNUM: A CASE REPORT AND LITERATURE REVIEW.Acta clinica Croatica · 2024Review
- Novel classification of gastric polyps: The good, the bad and the ugly.World journal of gastroenterology · 2024Article
- Heterotopic pancreas in the gallbladder: A case report.World journal of clinical cases · 2024Article
- Acute on chronic pancreatitis affecting the ectopic pancreas located in the jejunal mesentery: A case report.Acta radiologica open · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant transformation of ectopic pancreas tissue is a diagnostic challenge as clinical symptoms and radiographic features of these tumors are non-specific. Given the rarity of these lesions, it is usually neither suspected nor included in the diagnostic workup of different tumors. We conducted a comprehensive literature review regarding malignancy arising from ectopic pancreas for a better understanding of its frequency, clinicopathological features, and prognosis. A literature search was performed in three major databases: PubMed, Cochrane, and Web of Science. Fifty-four well-documented cases of malignant ectopic pancreas were identified in the published literature. Our analysis provided the following observations: (1) there was a slight predominance of males over females; (2) most patients with malignant transformation of ectopic pancreas were middle-aged; (3) most commonly, the tumor was located in the stomach; (4) most tumors were adenocarcinomas; (5) most frequently, the malignancy arose within a type I heterotopia according to Heinrich classification; (6) macroscopically, a subepithelial-like appearance was most frequently observed; and (7) improved prognosis for ectopic pancreatic malignancies in comparison with reported survival data for orthotopic pancreatic cancer. Even if the majority of cases of ectopic pancreas are incidental findings and malignant transformation is a rare event, pancreatic heterotopy should be considered as a source of potentially malignant lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.