Evidence map›Paper›PMID 30415277›Full record

ArticlePsychopharmacology2019

No effect of attentional bias modification training in methamphetamine users receiving residential treatment.

Andy C Dean, Erika L Nurmi, Scott J Moeller, Nader Amir, Michelle Rozenman, Dara G Ghahremani, Maritza Johnson, Robert Berberyan, Gerhard Hellemann, Ziwei Zhang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Challenges When Evaluating Cognitive Bias Modification Interventions for Substance Use Disorder.International journal of environmental research and public health · 2020
    Article
  6. A Scoping Review on Cue Reactivity in Methamphetamine Use Disorder.International journal of environmental research and public health · 2020
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Andy C DeanDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Erika L NurmiDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Scott J MoellerDepartment of Psychiatry, Stony Brook University School of Medicine, Stony Brook, NY, 11794, USA.
Nader AmirDepartment of Psychology, San Diego State University, San Diego, CA, 92120, USA.
Michelle RozenmanDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Dara G GhahremaniDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Maritza JohnsonDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Robert BerberyanDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Gerhard HellemannDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Ziwei ZhangDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA.
Edythe D LondonDepartment of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, David Geffen School of Medicine, Los Angeles, CA, 90024, USA. elondon@mednet.ucla.edu.
MIND Research Institute · USSan Diego State University · USStony Brook University · US

Funding

Genetic markers associated with brain structural abnormalities and drug use in human addictionK01DA037452 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOELLER, SCOTT J · 2015 to 2019
$778k
Attentional Bias Modification in Methamphetamine Use DisorderR21DA040156 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE DANICK · 2015 to 2016
$541k
Marjorie M. Greene Trust n/aNational Institute on Drug Abuse K01DA037452National Institute on Drug Abuse R21DA040156NIDA NIH HHS K01 DA037452NIDA NIH HHS R21 DA040156Thomas P and Katherine K Pike n/a
6 · The paper itself

Abstract

rationaleAttentional bias toward drug-related stimuli is a feature of drug addiction that is linked to craving and drug-seeking behavior. OBJECTIVES/

methodAn attentional bias modification (ABM) program was tested in 42 methamphetamine-dependent clients (DSM-IV criteria) receiving residential treatment for their drug use. Participants were randomly assigned to one of two groups (N = 21 each), receiving 12 sessions of either computerized ABM training (designed to train attention away from methamphetamine stimuli 100% of the time) or an attentional control condition (designed to train attention away from methamphetamine stimuli 50% of the time). Outcome measures included attentional bias to methamphetamine-related stimuli on a probe detection task, self-reported craving, and preferences to view methamphetamine-related images on a Simulated Drug Choice Task. A subset of participants (N = 17) also underwent fMRI in a cue-induced craving paradigm.

resultsPoor split-half reliability was observed for the probe detection task. Using this task, attentional bias toward methamphetamine-related stimuli was greater after training than at baseline, irrespective of group (p = 0.037). Spontaneous and cue-induced methamphetamine craving diminished with time (ps < 0.01), but ABM training did not influence these effects (group by time interactions, ps > 0.05). ABM training did not influence selection of methamphetamine-related pictures in the Simulated Drug Choice task (p > 0.05). In the fMRI assessment, cue-induced activation in the ventromedial prefrontal cortex was reduced over time, without an effect of ABM training.

conclusionsABM training did not improve several clinically relevant variables in treatment-seeking methamphetamine users. Additional research is needed to improve the measurement of attentional bias.

Indexed as

AdultAmphetamine-Related DisordersAttentional BiasCentral Nervous System StimulantsCravingFemaleHumansMagnetic Resonance ImagingMaleMethamphetaminePhotic StimulationReproducibility of ResultsResidential TreatmentSelf ReportCentral Nervous System StimulantsMethamphetamineAttentional biasCravingStimulantSubstance abuse

Identifiers

PMID30415277
PMCPMC6415773
OpenAlexW2899568001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.