Evidence map›Paper›PMID 30414785›Full record

Trial reportCanadian journal of diabetes2019

Effect of Aerobic and Resistance Exercise on Glycemic Control in Adults With Type 1 Diabetes.

Ravi Reddy, Amanda Wittenberg, Jessica R Castle, Joseph El Youssef, Kerri Winters-Stone, Melanie Gillingham, Peter G Jacobs

3 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Canadian journal of diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05107544 nacompletednot on this mapstarted 2021, after this paper: background citation

Metabolic, Physical Fitness and Mental Health Effects of High Intensity Interval Training (HIIT) in Adolescents With Type 1 Diabetes

TypeinterventionalSponsorHospital Las HiguerasRan2021 to 2022Enrolled30ConditionsDiabetes Mellitus, Type 1ArmsHIGH INTENSITY INTERVAL TRAINING
NCT05736263 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Setting a New Algorithm For the Management of Exercise-induced Glycemic Variations in Patients With Type 1 Diabetes in Intensive Therapy With Hybrid Closed-loop Systems

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2023 to 2024Enrolled50ConditionsType 1 Diabetes, ExerciseArmsModerate intensity exercise, High intensity interval exercise, Combined exercise, Resistance exercise
NCT06676878 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Assessment of Differences in Body Composition, Physical Fitness, and Thermoregulatory Response to Incremental Exercise in Young Boys With Type I Diabetes and Healthy Soccer Players

TypeinterventionalSponsorPaweł KormanRan2026 to 2027Enrolled40ConditionsDiabetesArmsIncremental exercise
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Preclinical techniques to investigate exercise training in vascular pathophysiology.American journal of physiology. Heart and circulatory physiology · 2021
    Pooled it
  3. Pooled it
  4. Guideline
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Tailoring Exercise Prescription for Effective Diabetes Glucose Management.The Journal of clinical endocrinology and metabolism · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ravi ReddyDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, USA.
Amanda WittenbergDepartment of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, USA.
Jessica R CastleDepartment of Medicine, Division of Endocrinology, Harold Schnitzer Diabetes Health Center, Oregon Health & Science University, Portland, Oregon, USA.
Joseph El YoussefDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, USA; Department of Medicine, Division of Endocrinology, Harold Schnitzer Diabetes Health Center, Oregon Health & Science University, Portland, Oregon, USA.
Kerri Winters-StoneSchool of Nursing, Human Performance Laboratory, Oregon Health and Science University, Portland, Oregon, USA.
Melanie GillinghamDepartment of Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon, USA.
Peter G JacobsDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, USA. Electronic address: jacobsp@ohsu.edu.
Oregon Health & Science University · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Mitigating risk in a closed loop system by exercise detection and miniaturizationDP3DK101044 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI CASTLE, JESSICA R, JACOBS, PETER G · 2013 to 2013
$2.9M
National Center for Advancing Translational Sciences UL1 TR002369National Institute of Diabetes and Digestive and Kidney Diseases DP3 DK101044NCATS NIH HHS UL1 TR002369NIDDK NIH HHS DP3 DK101044
6 · The paper itself

Abstract

objectivesPhysical exercise is recommended for individuals with type 1 diabetes, yet the effects of exercise on glycemic control are not well established. We evaluated the impact of different modes of exercise on glycemic control in people with type 1 diabetes.

methodsIn a 3-week randomized crossover trial, 10 adults with type 1 diabetes (4 men and 6 women, aged 33±6 years; duration of diabetes, 18±10 years; glycated hemoglobin level, 7.4%±1%) were assigned to 3 weeks of intervention: aerobic exercise (treadmill at 60% of maximum volume of oxygen utilization), resistance training (8 to 12 repetitions of 5 upper and lower body exercises at 60% to 80% of 1 repetition maximum) or no exercise (control). During each exercise week, participants completed 2 monitored 45 min exercise sessions. For each week of the study, we analyzed participants' insulin pump data, sensor glucose data and meal intake using a custom smart-phone application. The primary outcome was the percentage of time in range (glucose >3.9 mmol/L and ≤10 mmol/L) for the 24 h after each bout of exercise or rest during the control week. The study was registered on ClinicalTrials.gov (NCT:02687893).

resultsAerobic exercise caused a mean glucose reduction during exercise of 3.94±2.67 mmol/L, whereas the reduction during resistance training was 1.33±1.78 mmol/L (p=0.007). The mean percentage time in range for the 24 h after resistance training was significantly greater than that during the control period (70% vs. 56%, p=0.013) but not after aerobic exercise (60%).

conclusionsThe results indicate that when various confounders are considered, resistance training could improve glycemic control in this population.

Indexed as

ExerciseResistance TrainingAdultCross-Over StudiesDiabetes Mellitus, Type 1FemaleFollow-Up StudiesHumansHyperglycemiaHypoglycemiaMalePatient CompliancePrognosisapport alimentairedépense énergétiquediabète de type 1energy expenditureexerciceexerciseglycemic controlmeal intakerégulation de la glycémietype 1 diabetes

Identifiers

PMID30414785
PMCPMC6591112
OpenAlexW2889124544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.