Evidence map›Paper›PMID 30414397›Full record

ArticleAmerican journal of ophthalmology2019

Glaucoma Specialist Detection of Optical Coherence Tomography Suspicious Rim Tissue in Glaucoma and Glaucoma Suspect Eyes.

Seung Woo Hong, Helen Koenigsman, Hongli Yang, Ruojin Ren, Juan Reynaud, Robert M Kinast, Steven L Mansberger, Brad Fortune, Shaban Demirel, Stuart K Gardiner and 1 more

Abstract readComparative Study
In one paragraph

Article in American journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Seung Woo HongOptic Nerve Head Research Laboratory, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA; Department of Ophthalmology, Medical College, the Catholic University of Korea, Seoul, South Korea.
Helen KoenigsmanOptic Nerve Head Research Laboratory, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Hongli YangOptic Nerve Head Research Laboratory, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Ruojin RenOptic Nerve Head Research Laboratory, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Juan ReynaudOptic Nerve Head Research Laboratory, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA; Discoveries in Sight Research Laboratories, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Robert M KinastDevers Eye Institute Glaucoma Service, Portland, Oregon, USA.
Steven L MansbergerDiscoveries in Sight Research Laboratories, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA; Devers Eye Institute Glaucoma Service, Portland, Oregon, USA.
Brad FortuneDiscoveries in Sight Research Laboratories, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Shaban DemirelDiscoveries in Sight Research Laboratories, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Stuart K GardinerDiscoveries in Sight Research Laboratories, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA.
Claude F BurgoyneOptic Nerve Head Research Laboratory, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA; Discoveries in Sight Research Laboratories, Devers Eye Institute, Legacy Research Institute, Portland, Oregon, USA; Devers Eye Institute Glaucoma Service, Portland, Oregon, USA. Electronic address: cfburgoyne@deverseye.org.
Legacy Health · USCatholic University of Korea · KR

Funding

Optic Nerve Head SDOCT Imaging in GlaucomaR01EY021281 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI BURGOYNE, CLAUDE F · 2011 to 2018
$3.7M
Predicting the rate of progression in glaucomaR01EY019674 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI DEMIREL, SHABAN · 2009 to 2013
$1.8M
NEI NIH HHS R01 EY019674NEI NIH HHS R01 EY021281
6 · The paper itself

Abstract

purposeTo assess glaucoma specialists' detection of optic nerve head (ONH) rim tissue that is thin by optical coherence tomography (OCT) criteria.

designReliability analysis.

methodsFive clinicians marked the disc margin (DM) and rim margin (RM) on stereophotographs of 151 glaucoma or glaucoma suspect eyes obtained within 3 months of OCT imaging. The photo and OCT infrared image for each eye were co-localized and regionalized into 12 sectors relative to the axis between the Bruch membrane opening (BMO) centroid and the fovea. For each clinician, the distance from BMO centroid to their DM (DM radius) and RM (RM radius) was used to generate sectoral rim width (RW) (DM radius-RM radius) and cup-to-disc ratio (CDR) (RM radius/DM radius) estimates. OCT minimum rim width (MRW) was determined by sector. Among all eyes, for each OCT MRW suspicious sector (<5% of OCT normative database), we determined each clinician's detection (clinician CDR ≥ 0.7).

resultsClinicians most commonly failed to detect OCT suspicious rim tissue in the nasal sectors. Among 502 sectors with suspicious OCT MRW, all 5 clinicians rated CDR ≥ 0.7 in only 29.5% and all 5 clinicians rated CDR < 0.7 in 21%. OCT suspicious rim thickness was most common (32% of eyes) in the nasal and inferior sectors. MRW vs clinician RW discordance was greatest nasally, while BMO vs clinician DM discordance was greatest temporally.

conclusionsClinicians most commonly failed to detect OCT suspicious rim thickness nasally where suspicious rim tissues were also most common.

Indexed as

AdultAgedAged, 80 and overBruch MembraneFemaleGlaucoma, Open-AngleHumansIntraocular PressureMaleMiddle AgedNerve FibersOcular HypertensionOptic DiskReproducibility of ResultsRetinal Ganglion CellsSpecialization

Identifiers

PMID30414397
PMCPMC6382546
OpenAlexW2899738608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.