Evidence map›Paper›PMID 30414126›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Mutagenesis and Imaging Studies of BMP Signaling Mechanisms in C. elegans.

Cathy Savage-Dunn, Ryan J Gleason, Jun Liu, Richard W Padgett

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. bioRxiv : the preprint server for biology · 2023
    Article
  4. Article
  5. Tetraspanins TSP-12 and TSP-14 function redundantly to regulate the trafficking of the type II BMP receptor inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cathy Savage-DunnDepartment of Biology, Queens College, CUNY, Flushing, NY, USA.
Ryan J GleasonDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Jun LiuDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Richard W PadgettDepartment of Molecular Biology and Biochemistry, Waksman Institute, Rutgers University, Piscataway, NJ, USA. padgett@waksman.rutgers.edu.

Funding

Mesodermal Cell Fate Specification in C.elegansR01GM066953 · NIGMS · CORNELL UNIVERSITY ITHACA · PI LIU, JUN · 2002 to 2016
$3.9M
Molecular mechanisms modulating BMP signalingR01GM103869 · NIGMS · CORNELL UNIVERSITY · PI LIU, JUN · 2014 to 2017
$1.2M
Intercellular Signaling and Endosome to Golgi Transport in Multicellular AnimalsR01GM103995 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI GRANT, BARTH DEMIAN, PADGETT, RICHARD W. · 2013 to 2016
$1.2M
Regulation of Metabolism by C. Elegans DBL-1/BMP SignalingR15GM112147 · NIGMS · QUEENS COLLEGE · PI SAVAGE-DUNN, CATHY · 2015 to 2019
$832k
NIGMS NIH HHS R01 GM066953NIGMS NIH HHS R01 GM103869NIGMS NIH HHS R01 GM103995NIGMS NIH HHS R15 GM112147
6 · The paper itself

Abstract

C. elegans has played a central role in the elucidation of the TGFβ pathway over the last two decades. This is due to the high conservation of the pathway components and the power of genetic and cell biological approaches applied toward understanding how the pathway signals. In Subheading 3, we detail approaches to study the BMP branch of the TGFβ pathway in C. elegans.

Indexed as

Molecular ImagingMutagenesisSignal TransductionAnimalsBone Morphogenetic ProteinsCaenorhabditis elegansCaenorhabditis elegans ProteinsGenetic TestingMesodermMutationBone Morphogenetic ProteinsCaenorhabditis elegans ProteinsBody sizeC. elegansCoelomocytesDevelopmentGenetic screensImagingMesodermMutagenesisTrafficking

Identifiers

PMID30414126
PMCPMC6731545

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.