Evidence map›Paper›PMID 30414017›Full record

ArticleJournal of molecular neuroscience : MN2018

Insulin-Like Growth Factor-1 Alleviates Expression of Aβ

Fangfang Song, Tingting Liu, Songyan Meng, Fengqing Li, Yina Zhang, Lihong Jiang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Role of the Insulin-like Growth Factor System in Neurodegenerative Disease.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Physical Exercise-Induced Myokines in Neurodegenerative Diseases.International journal of molecular sciences · 2021
    Review
  8. Metformin Ameliorates AOxidative medicine and cellular longevity · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fangfang SongDepartment of Geriatric, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang, People's Republic of China.
Tingting LiuDepartment of Geriatric, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang, People's Republic of China.
Songyan MengDepartment of Geriatric, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang, People's Republic of China.
Fengqing LiDepartment of Geriatric, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang, People's Republic of China.
Yina ZhangDepartment of Geriatric, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang, People's Republic of China. wa147311@sohu.com.ORCID http://orcid.org/0000-0002-2397-2182
Lihong JiangDepartment of General Practice, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang, People's Republic of China. jianglihong2006@163.com.
Harbin Medical University · CN

Funding

Scientific Research Foundation for the Returned Overseas Scholars of Heilongjiang Province LC2009C13Young Scholar of the Second Affiliated Hospital of Harbin Medical University QN2012-08
6 · The paper itself

Abstract

To examine the effect of subcutaneous injection of insulin-like growth factor-1 (IGF-1) on the expression of the amyloid protein (Aβ

Indexed as

ADAM10 ProteinAlzheimer DiseaseAmyloid beta-PeptidesAmyloid Precursor Protein SecretasesAnimalsAspartic Acid EndopeptidasesCerebral CortexHippocampusInsulin-Like Growth Factor IMembrane ProteinsMicePeptide FragmentsPresenilin-1ADAM10 ProteinAdam10 protein, mouseAmyloid beta-Peptidesamyloid beta-protein (1-40)Amyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesBace1 protein, mouseInsulin-Like Growth Factor IMembrane ProteinsPeptide FragmentsPresenilin-1Alzheimer’s diseaseAPP/PS1 double transgenic mouseAβ1–40IGF-1Secretase of the amyloid precursor protein

Identifiers

PMID30414017
OpenAlexW2900373846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.