Evidence map›Paper›PMID 30413995›Full record

ArticleCell stress & chaperones2019

Role of a serine protease gene (AccSp1) from Apis cerana cerana in abiotic stress responses and innate immunity.

Lijun Gao, Lijun Wang, Xinxin Yang, Ying Wang, Zhenguo Liu, Baohua Xu, Xingqi Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell stress & chaperones, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Climate change-induced stress in the honey beeFrontiers in physiology · 2025
    Review
  4. Article
  5. Article
  6. Clip-Domain Serine Protease Gene (Frontiers in physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lijun GaoState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China.
Lijun WangState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China.
Xinxin YangState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China.
Ying WangCollege of Animal Science and Technology, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China.
Zhenguo LiuCollege of Animal Science and Technology, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China.
Baohua XuCollege of Animal Science and Technology, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China. bhxu@sdau.edu.cn.
Xingqi GuoState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, 271018, Shandong, People's Republic of China. xqguo@sdau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clip-domain serine proteases (Clip-SPs) mediate innate immunity and embryonic development in insects. However, the function of Clip-SPs in Apis cerana cerana is little known. Here, a Clip-SP gene, AccSp1, was identified. AccSp1 was mainly detected in third and sixth day instar larvae, dark-eyed pupae, and adults (1and 30 days post-emergence). In addition, AccSp1 was expressed at its highest level in the venom gland and epidermis than tentacle, abdomen, muscle, honey sac, head, leg, chest, hemolymph, rectum, and midgut. AccSp1 was induced by 4, 24, and 44 °C; H

Indexed as

Amino Acid SequenceAnimalsBeesGene Expression Regulation, DevelopmentalGene Knockdown TechniquesImmunity, InnateInsect ProteinsMetabolomeMonophenol MonooxygenasePhylogenyRNA InterferenceRNA, MessengerSerine ProteasesStress, PhysiologicalSurvival AnalysisInsect ProteinsMonophenol MonooxygenaseRNA, MessengerSerine ProteasesAbiotic stressesAntioxidant enzymeApis cerana ceranaClip-domain serine proteasePO activityRNA interference

Identifiers

PMID30413995
PMCPMC6363618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.