Evidence map›Paper›PMID 30413889›Full record

ReviewWorld journal of microbiology & biotechnology2018

Recent advances and future trends of riboswitches: attractive regulatory tools.

Jean Paul Sinumvayo, Chunhua Zhao, Philibert Tuyishime

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. TheRNA (New York, N.Y.) · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. A Riboswitch-Driven Era of New Antibacterials.Antibiotics (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jean Paul SinumvayoCAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China. sinipaul2014@yahoo.fr.
Chunhua ZhaoCAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Philibert TuyishimeUniversity of Chinese Academy of Sciences, Beijing, China.
University of Chinese Academy of Sciences · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial genomes contain a huge amount of different genes. These genes are spatiotemporally expressed to accomplish some required functions within the organism. Inside the cell, any step of gene expression may be modulated at four possible places such as transcription initiation, translation regulation, mRNA stability and protein stability. To achieve this, there is a necessity of strong regulators either natural or synthetic which can fine-tune gene expression regarding the required function. In recent years, riboswitches as metabolite responsive control elements residing in the untranslated regions of certain messenger RNAs, have been known to control gene expression at transcription or translation level. Importantly, these control elements do not prescribe the involvement of protein factors for metabolite binding. However, they own their particular properties to sense intramolecular metabolites (ligands). Herein, we highlighted current important bacterial riboswitches, their applications to support genetic control, ligand-binding domain mechanisms and current progress in synthetic riboswitches.

Indexed as

Gene Expression Regulation, BacterialAptamers, NucleotideAptamers, PeptideBacteriaBacterial ProteinsGenes, BacterialGlutamine-Fructose-6-Phosphate Transaminase (Isomerizing)GlycineLigandsPyrimidinonesPyrrolesRiboswitchRNA, Bacterial7-(aminomethyl)-7-deazaguanineAptamers, NucleotideAptamers, PeptideBacterial Proteinscomponent S, glutamate mutase protein, BacteriaGlutamine-Fructose-6-Phosphate Transaminase (Isomerizing)GlycineLigandsPyrimidinonesPyrrolesRiboswitchRNA, BacterialAptamer domainExpression platformGene expressionmRNA 5′-UTRRiboswitches

Identifiers

PMID30413889
OpenAlexW2899925760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.