Evidence map›Paper›PMID 30413880›Full record

ArticleLangenbeck's archives of surgery2018

Thoracoscopic esophagectomy with total meso-esophageal excision reduces regional lymph node recurrence.

Yuji Akiyama, Takeshi Iwaya, Fumitaka Endo, Haruka Nikai, Kei Sato, Shigeaki Baba, Takehiro Chiba, Toshimoto Kimura, Takeshi Takahara, Koki Otsuka and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Langenbeck's archives of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Imaging in Esophageal Cancer: A Comprehensive Review.The Indian journal of radiology & imaging · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Efficacy of enhanced prehabilitation for patients with esophageal cancer undergoing esophagectomy.Esophagus : official journal of the Japan Esophageal Society · 2021
    Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuji AkiyamaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan. yakiyama@iwate-med.ac.jp.ORCID http://orcid.org/0000-0001-5658-7419
Takeshi IwayaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Fumitaka EndoDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Haruka NikaiDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Kei SatoDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Shigeaki BabaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Takehiro ChibaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Toshimoto KimuraDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Takeshi TakaharaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Koki OtsukaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Hiroyuki NittaDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Masaru MizunoDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.
Yusuke KimuraDepartment of Palliative Medicine, Iwate Medical University School of Medicine, Iwate, Japan.
Keisuke KoedaDepartment of Medical Safety Science, Iwate Medical University School of Medicine, Iwate, Japan.
Akira SasakiDepartment of Surgery, Iwate Medical University School of Medicine, 19-1 Uchimaru MoriokaIwate, 020-8505, Iwate, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated the operative outcomes of thoracoscopic esophagectomy (TE) in the prone position, using the concept of total meso-esophageal excision for esophageal cancer.

methodsThe medical records of 140 consecutive patients with esophageal cancer who underwent radical esophagectomy by TE were reviewed retrospectively, and operative outcomes were compared between patients treated before (non-meso-esophagus; non-ME group) and after (ME group) the introduction of total meso-esophageal excision (ME).

resultsThere were no significant differences between the groups in postoperative morbidity (non-ME group vs. ME group, 28.3% vs. 41.4%, p = 0.119), 30-day mortality (non-ME group vs. ME group, 0% vs. 1.1%; p = 0.433), and in-hospital mortality (non-ME group vs. ME group, 1.9% vs. 0%, p = 0.199). Although overall survival and relapse-free survival did not differ significantly between the groups, the overall recurrence rate was significantly lower in the ME group than the non-ME group (non-ME group vs. ME group, 43.4% vs. 23%, p = 0.011). In particular, the rate of regional lymph node recurrence in the mediastinum was lower in the ME group (non-ME group vs. ME group, 11.3% vs. 2.3%; p = 0.026).

conclusionsOur results suggest that the ME procedure might be one of the procedures that reduce regional lymph node recurrence in the mediastinum without any deterioration in short-term outcomes.

Indexed as

EsophagectomyLymph Node ExcisionThoracoscopyAgedEsophageal NeoplasmsFemaleHumansLymphatic MetastasisMaleMiddle AgedPatient PositioningProne PositionRetrospective StudiesTreatment OutcomeEsophageal cancerMeso-esophagusMinimally invasive esophagectomyPreceding anterior approachThoracoscopic esophagectomy

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.