Evidence map›Paper›PMID 30413857›Full record

ArticlePediatric radiology2019

Ultrafast pediatric chest computed tomography: comparison of free-breathing vs. breath-hold imaging with and without anesthesia in young children.

Aya Kino, Evan J Zucker, Anita Honkanen, Jerry Kneebone, Jia Wang, Frandics Chan, Beverley Newman

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  14. Paediatric CT made easy.Pediatric radiology · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aya KinoDepartment of Radiology, Lucile Packard Children's Hospital at Stanford University, 725 Welch Road, Room 1677 MC 5913, Stanford, CA, 94304, USA. Akino2@stanford.edu.ORCID http://orcid.org/0000-0002-9824-2184
Evan J ZuckerDepartment of Radiology, Lucile Packard Children's Hospital at Stanford University, 725 Welch Road, Room 1677 MC 5913, Stanford, CA, 94304, USA.
Anita HonkanenDepartment of Anesthesia, Lucile Packard Children's Hospital at Stanford University, Stanford, CA, USA.
Jerry KneeboneDepartment of Radiology, Lucile Packard Children's Hospital at Stanford University, 725 Welch Road, Room 1677 MC 5913, Stanford, CA, 94304, USA.
Jia WangEnvironmental Health and Safety, Stanford University, Stanford, CA, USA.
Frandics ChanDepartment of Radiology, Lucile Packard Children's Hospital at Stanford University, 725 Welch Road, Room 1677 MC 5913, Stanford, CA, 94304, USA.
Beverley NewmanDepartment of Radiology, Lucile Packard Children's Hospital at Stanford University, 725 Welch Road, Room 1677 MC 5913, Stanford, CA, 94304, USA.
Lucile Packard Children's Hospital · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneral anesthesia (GA) or sedation has been used to obtain good-quality motion-free breath-hold chest CT scans in young children; however pulmonary atelectasis is a common and problematic accompaniment that can confound diagnostic utility. Dual-source multidetector CT permits ultrafast high-pitch sub-second examinations, minimizing motion artifact and potentially eliminating the need for a breath-hold.

objectiveThe purpose of this study was to evaluate the feasibility of free-breathing ultrafast pediatric chest CT without GA and to compare it with breath-hold and non-breath-hold CT with GA. MATERIALS AND

methodsYoung (≤3 years old) pediatric outpatients scheduled for chest CT under GA were recruited into the study and scanned using one of three protocols: GA with intubation, lung recruitment and breath-hold; GA without breath-hold; and free-breathing CT without anesthesia. In all three protocols an ultrafast high-pitch CT technique was used. We evaluated CT images for overall image quality, presence of atelectasis and motion artifacts.

resultsWe included 101 scans in the study. However the GA non-breath-hold technique was discontinued after 15 scans, when it became clear that atelectasis was a major issue despite diligent attempts to mitigate it. This technique was therefore not included in statistical evaluation (86 remaining patients). Overall image quality was higher (P=0.001) and motion artifacts were fewer (P<.001) for scans using the GA with intubation and recruitment technique compared to scans in the non-GA free-breathing group. However no significant differences were observed regarding the presence of atelectasis between these groups.

conclusionWe demonstrated that although overall image quality was best and motion artifact least with a GA-breath-hold intubation and recruitment technique, free-breathing ultrafast pediatric chest CT without anesthesia provides sufficient image quality for diagnostic purposes and can be successfully performed both without and with contrast agent in young infants.

Indexed as

Anesthesia, GeneralArtifactsBreath HoldingChild, PreschoolFeasibility StudiesFemaleHumansInfantMaleProspective StudiesPulmonary AtelectasisRadiography, ThoracicRespirationRetrospective StudiesTomography, X-Ray ComputedAnesthesiaChestChildrenComputed tomographyFree breathing

Identifiers

PMID30413857
OpenAlexW2899621406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.