Evidence map›Paper›PMID 30413767›Full record

ArticleScientific reports2018

Cardioprotective Effects of Curcumin-Nisin Based Poly Lactic Acid Nanoparticle on Myocardial Infarction in Guinea Pigs.

Williams E E Nabofa, Oluwadamilola O Alashe, Oyetunde T Oyeyemi, Alfred F Attah, Ademola A Oyagbemi, Temidayo O Omobowale, Adeolu A Adedapo, Akinola R A Alada

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
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  7. Biodegradable Polymers in Veterinary Medicine-A Review.Molecules (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Review
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  11. Review
  12. Review
  13. Article
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  15. Article
  16. Article
  17. Animal models used in the research of nanoparticles for cardiovascular diseases.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2021
    Review
  18. Review
  19. Obstacles against the Marketing of Curcumin as a Drug.International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Williams E E NabofaDepartment of Physiology, Bencarson (Snr) School of Medicine, Babcock University, Ilishan-Remo, Nigeria. williamsnab@yahoo.com.ORCID http://orcid.org/0000-0002-4491-2445
Oluwadamilola O AlasheDepartment of Physiology, Bencarson (Snr) School of Medicine, Babcock University, Ilishan-Remo, Nigeria.
Oyetunde T OyeyemiDepartment of Biological Sciences, University of Medical Sciences, Ondo, Ondo State, Nigeria.
Alfred F AttahDepartment of Pharmacognosy, University of Ibadan, Ibadan, Nigeria.
Ademola A OyagbemiDepartment of Veterinary Physiologv and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Temidayo O OmobowaleDepartment of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Adeolu A AdedapoDepartment of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Akinola R A AladaDepartment of Physiology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
University of Ibadan · NGBabcock University · NGUniversity of Medical Sciences, Ondo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is the most prevalent cause of cardiovascular death. A possible way of preventing MI maybe by dietary supplements. The present study was thus designed to ascertain the cardio-protective effect of a formulated curcumin and nisin based poly lactic acid nanoparticle (CurNisNp) on isoproterenol (ISO) induced MI in guinea pigs. Animals were pretreated for 7 days as follows; Groups A and B animals were given 0.5 mL/kg of normal saline, group C metoprolol (2 mg/kg), groups D and E CurNisNp 10 and 21 mg/kg respectively (n = 5). MI was induced on the 7

Indexed as

Drug Delivery SystemsAdrenergic beta-AgonistsAnimalsAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalCardiotonic AgentsCurcuminDrug Therapy, CombinationGuinea PigsIsoproterenolMaleMyocardial InfarctionNanoparticlesNisinPolyestersAdrenergic beta-AgonistsAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalCardiotonic AgentsCurcuminIsoproterenolNisinPolyesterspoly(lactide)

Identifiers

PMID30413767
PMCPMC6226538
OpenAlexW2900325739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.