Evidence map›Paper›PMID 30413707›Full record

ArticleNature communications2018

Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling.

Lei Zhang, Chi Kin Ip, I-Chieh J Lee, Yue Qi, Felicia Reed, Tim Karl, Jac Kee Low, Ronaldo F Enriquez, Nicola J Lee, Paul A Baldock and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 66 citations in OpenAlex.

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  15. Hypothalamic control of energy expenditure and thermogenesis.Experimental & molecular medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Lei ZhangNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.ORCID http://orcid.org/0000-0002-3927-8881
Chi Kin IpNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.
I-Chieh J LeeNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.
Yue QiNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.
Felicia ReedNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.
Tim KarlSchool of Medicine, Western Sydney University, Sydney, NSW, Australia.
Jac Kee LowNeuroscience Research Australia, Randwick, NSW, Australia.ORCID http://orcid.org/0000-0002-7416-8645
Ronaldo F EnriquezNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.
Nicola J LeeNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia.
Paul A BaldockSchool of Medical Sciences, University of NSW, Sydney, NSW, Australia.
Herbert HerzogNeuroscience Division, Garvan Institute of Medical Research, St. Vincent's Hospital, Darlinghurst, NSW, Australia. h.herzog@garvan.org.au.ORCID http://orcid.org/0000-0002-1713-1029
Garvan Institute of Medical Research · AUNeuroscience Research Australia · AUWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms controlling these processes are unclear. Here we identify the neuropeptide FF receptor-2 (NPFFR2) as a critical regulator of diet-induced thermogenesis and bone homoeostasis. Npffr2

Indexed as

DietSignal TransductionThermogenesisAdipose Tissue, BrownAnimalsArcuate Nucleus of HypothalamusBehavior, AnimalBone and BonesCold TemperatureEnergy MetabolismFemaleHomeostasisLigandsMaleMice, KnockoutNeuronsarginylphenylalaninamideLigandsneuropeptide FF receptorNeuropeptidesNeuropeptide YReceptors, NeuropeptideRNA, Messenger

Identifiers

PMID30413707
PMCPMC6226433
OpenAlexW2900370600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.