Evidence map›Paper›PMID 30413672›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus-Specific CD8

Alba Grifoni, Priscilla Costa-Ramos, John Pham, Yuan Tian, Sandy L Rosales, Grégory Seumois, John Sidney, Aruna D de Silva, Lakshmanane Premkumar, Matthew H Collins and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 9 institutions in 4 countries.

Alba GrifoniDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.ORCID 0000-0002-2209-5966
Priscilla Costa-RamosDivision of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil.
John PhamDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Yuan TianDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Sandy L RosalesDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Grégory SeumoisDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.ORCID 0000-0002-8164-6852
John SidneyDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.ORCID 0000-0002-0987-405X
Aruna D de SilvaDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.ORCID 0000-0001-5291-9543
Lakshmanane PremkumarDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27516.
Matthew H CollinsDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27516.ORCID 0000-0001-7974-1933
Mars StoneBlood Systems Research Institute, San Francisco, CA 94118.ORCID 0000-0001-5619-2767
Phillip J NorrisBlood Systems Research Institute, San Francisco, CA 94118.ORCID 0000-0003-0526-2088
Claudia M E RomeroUniversidad del Norte, Barranquilla 1569, Colombia.ORCID 0000-0001-7860-5542
Anna DurbinSchool of Medicine, University of Vermont, Burlington, VT 05405.ORCID 0000-0002-6652-2851
Michael J RicciardiDepartment of Pathology, Miller School of Medicine, University of Miami, Miami, FL 33146.
Julie E LedgerwoodVaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
Aravinda M de SilvaDepartment of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27516.
Michael BuschBlood Systems Research Institute, San Francisco, CA 94118.ORCID 0000-0002-1446-125X
Bjoern PetersDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.ORCID 0000-0002-8457-6693
Pandurangan VijayanandDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Eva HarrisDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, CA 94720.ORCID 0000-0002-7238-4037
Andrew K FalconarUniversidad del Norte, Barranquilla 1569, Colombia.ORCID 0000-0002-2066-9487
Esper KallasDivision of Clinical Immunology and Allergy, School of Medicine, University of São Paulo, São Paulo 01246-903, Brazil.ORCID 0000-0003-2026-6925
Daniela WeiskopfDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037; alex@lji.org.ORCID 0000-0001-7013-2250
La Jolla Institute for Immunology · USUniversity of North Carolina at Chapel Hill · USBlood Systems Research Institute · USUniversidad del Norte · COUniversidade de São Paulo · BRBerkeley Public Health Division · USNational Institute of Allergy and Infectious Diseases · USUniversity of Miami · USUniversity of Vermont · US

Funding

Single-cell atlas of lung tissue-resident memory T cells reactive to upper and lower respiratory tract pathogensU19AI118626 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Pandurangan Vijayanand · 2015 to 2026
$36.7M
T Cell Responses Following DENV Natural Infections and Live-Attenuated Dengue Virus VaccinationP01AI106695 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Aravinda M. DeSilva · 2015 to 2026
$34.1M
Illumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NCRR NIH HHS S10 RR027366NHLBI NIH HHS HHSN268201100001INIAID NIH HHS HHSN272200900042CNIAID NIH HHS HHSN272201400045CNIAID NIH HHS P01 AI106695NIAID NIH HHS U19 AI118626NIH HHS S10 OD016262WHI NIH HHS HHSN268201100001C
6 · The paper itself

Abstract

Zika virus (ZIKV) constitutes an increasing public health problem. Previous studies have shown that CD8

Indexed as

Antigens, ViralCD8-Positive T-LymphocytesCells, CulturedCytotoxicity, ImmunologicEpitopes, T-LymphocyteGene Expression ProfilingGranzymesHumansImmunoglobulinsImmunophenotypingInterferon-gammaReceptors, Tumor Necrosis FactorTumor Necrosis Factor-alphaZika VirusZika Virus InfectionAntigens, Viralclass-I restricted T cell-associated moleculeEpitopes, T-LymphocyteGranzymesGZMB protein, humanImmunoglobulinsInterferon-gammaReceptors, Tumor Necrosis FactorTumor Necrosis Factor-alpha

Identifiers

PMID30413672
PMCPMC6287102
OpenAlexW2899624540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.