ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Neurochemical and Behavioral Dissections of Decision-Making in a Rodent Multistage Task.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Dissociation of decision-making from escalated drug intake within a long-access model.Behavioural brain research · 2026Article
- Fentanyl reinforcement history has sex-specific effects on multi-step decision-making.Neuropharmacology · 2026Article
- The distinct functions of working memory and intelligence in model-based and model-free reinforcement learning.NPJ science of learning · 2025Article
- Disruptions in Reward-Guided Decision-Making Functions Are Predictive of Greater Oral Oxycodone Self-Administration in Male and Female Rats.Biological psychiatry global open science · 2025Article
- Complementary roles of serotonin and dopamine in model-based learning.Current opinion in behavioral sciences · 2025Article
- Dopamine Release in the Nucleus Accumbens Core Encodes the General Excitatory Components of Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Leveraging individual differences in cue-reward learning to investigate the psychological and neural basis of shared psychiatric symptomatology: The sign-tracker/goal-tracker model.Behavioral neuroscience · 2024Review
- Reward-Mediated, Model-Free Reinforcement-Learning Mechanisms in Pavlovian and Instrumental Tasks Are Related.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Opponent Learning with Different Representations in the Cortico-Basal Ganglia Circuits.eNeuro · 2023Article
- Review
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- The role of reinforcement learning and value-based decision-making frameworks in understanding food choice and eating behaviors.Frontiers in nutrition · 2022Review
- Dopamine enhances model-free credit assignment through boosting of retrospective model-based inference.eLife · 2021Article
- HIV Transgenic Rats Demonstrate Superior Task Acquisition and Intact Reversal Learning in the Within-Session Probabilistic Reversal Learning Task.Cognitive, affective & behavioral neuroscience · 2021Article
- Habit, choice, and addiction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Review
- The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection.Neuron · 2021Article
- Neural substrates of habit.Journal of neuroscience research · 2020Review
- Learning the structure of the world: The adaptive nature of state-space and action representations in multi-stage decision-making.PLoS computational biology · 2019Article
- Article
- Model-Free and Model-Based Influences in Addiction-Related Behaviors.Biological psychiatry · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Flexible decision-making in dynamic environments requires both retrospective appraisal of reinforced actions and prospective reasoning about the consequences of actions. These complementary reinforcement-learning systems can be characterized computationally with model-free and model-based algorithms, but how these processes interact at a neurobehavioral level in normal and pathological states is unknown. Here, we developed a translationally analogous multistage decision-making (MSDM) task to independently quantify model-free and model-based behavioral mechanisms in rats. We provide the first direct evidence that male rats, similar to humans, use both model-free and model-based learning when making value-based choices in the MSDM task and provide novel analytic approaches for independently quantifying these reinforcement-learning strategies. Furthermore, we report that
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.