Evidence map›Paper›PMID 30413536›Full record

ArticleThe Journal of biological chemistry2019

The structure of PilA from

Leslie A Ronish, Erik Lillehoj, James K Fields, Eric J Sundberg, Kurt H Piepenbrink

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. Review
  3. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  4. Ciprofloxacin resistance enhances biofilm formation and modulates virulence in Acinetobacter baumannii: Insights into the role of efflux pumps and quorum sensing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Review
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  8. Article
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  10. Article
  11. Article
  12. Phenotypic Characterization ofAntibiotics (Basel, Switzerland) · 2025
    Article
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  18. Article
  19. Signaling inComputational and structural biotechnology journal · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Leslie A RonishDepartment of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588.
Erik LillehojDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland 21201.
James K FieldsInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Eric J SundbergInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland 21201; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201; Departments of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Kurt H PiepenbrinkDepartment of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588; Departments of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, Nebraska 68588; Nebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, Nebraska 68588; Center for Integrated Biomolecular Communication, University of Nebraska-Lincoln, Lincoln, Nebraska 68588. Electronic address: kurt.piepenbrink@unl.edu.
University of Maryland, Baltimore · USUniversity of Nebraska–Lincoln · US

Funding

Targeted mass spectrometry approaches to understand CART processing and recepter interactionsP20GM113126 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI GUO, JIANTAO · 2016 to 2025
$20.8M
Structure & Function of Clostridium difficile Type IV PiliR01AI114902 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SUNDBERG, ERIC JOHN · 2015 to 2019
$2.6M
Structural Basis of Type IV Pilus-Induced Clostridium difficile Microcolony FormationK22AI123467 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI PIEPENBRINK, KURT HENRY · 2017 to 2018
$260k
NIAID NIH HHS K22 AI123467NIAID NIH HHS R01 AI114902NIGMS NIH HHS P20 GM113126
6 · The paper itself

Abstract

Type IV pili (T4P) are bacterial appendages composed of protein subunits, called pilins, noncovalently assembled into helical fibers. T4P are essential, in many bacterial species, for processes as diverse as twitching motility, natural competence, biofilm or microcolony formation, and host cell adhesion. The genes encoding type IV pili are found universally in the Gram-negative, aerobic, nonflagellated, and pathogenic coccobacillus

Indexed as

Acinetobacter baumanniiAmino Acid SubstitutionCrystallography, X-RayFimbriae ProteinsGlycosylationMutation, MissenseProtein DomainsFimbriae ProteinsAcinetobacterbacterial adhesionbacterial pathogenesisbiofilmelectrostaticshost-pathogen interactionstructural biologytwitching motilitytype IV piliX-ray crystallography

Identifiers

PMID30413536
PMCPMC6322890
OpenAlexW2899613162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.