Evidence map›Paper›PMID 30413416›Full record

ArticleG3 (Bethesda, Md.)2019

Domain Requirements and Genetic Interactions of the Mud1 Subunit of the

Radhika Agarwal, Beate Schwer, Stewart Shuman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Radhika AgarwalMolecular Biology Program, Sloan-Kettering Institute, New York, NY 10065.
Beate SchwerMicrobiology and Immunology Department, Weill Cornell Medical College, New York, NY 10065 bschwer@med.cornell.edu s-shuman@ski.mskcc.org.
Stewart ShumanMolecular Biology Program, Sloan-Kettering Institute, New York, NY 10065 bschwer@med.cornell.edu s-shuman@ski.mskcc.org.
Kettering University · USCornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
mRNA Capping EnzymesR01GM052470 · NIGMS · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SCHWER, BEATE, SHUMAN, STEWART H · 1995 to 2019
$9.9M
Mechanisms of DNA and RNA TransactionsR35GM126945 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Stewart H Shuman · 2018 to 2026
$8.9M
RNA caps and meiotic pre-mRNA splicingR01GM102961 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHWER, BEATE · 2013 to 2016
$1.3M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM052470NIGMS NIH HHS R01 GM102961NIGMS NIH HHS R35 GM126945
6 · The paper itself

Abstract

Mud1 is an inessential 298-amino acid protein subunit of the

Indexed as

AlanineAmino Acid SequenceEpistasis, GeneticProtein DomainsRibonucleoproteins, Small NuclearRibonucleoprotein, U1 Small NuclearRibonucleoprotein, U2 Small NuclearRNA SplicingRNA Splicing FactorsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence DeletionSpliceosomesSplicing Factor U2AFSynthetic Lethal MutationsAlanineMSL1 protein, S cerevisiaeMSL5 protein, S cerevisiaeMUD2 protein, S cerevisiaeNAM8 protein, S cerevisiaeRibonucleoproteins, Small NuclearRibonucleoprotein, U1 Small NuclearRibonucleoprotein, U2 Small NuclearRNA Splicing FactorsSaccharomyces cerevisiae ProteinsSplicing Factor U2AFU1A proteinmutagenesispre-mRNA splicingRRM domainssynthetic lethalityU1 snRNP

Identifiers

PMID30413416
PMCPMC6325900
OpenAlexW2900377736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.