ArticleImmunity2018
Interleukin-17-Producing γδ T Cells Originate from SOX13
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 64 papers.
0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 104 citations in OpenAlex.
- TDP-43 promotes allergen-induced inflammation and influenza A virus replication in airway epithelium.Nature communications · 2026Article
- Epithelial chemokine CCL25 integrates T cell development and intestinal homeostasis.The Journal of experimental medicine · 2026Article
- Tetrameric STAT5 regulates the formation of immune niche cells to protect stem cell regenerative repair against mucosal inflammation.Experimental & molecular medicine · 2026Article
- Single-cell transcriptomics reveals diversity and conservation of chicken lymphocytes.Poultry science · 2026Article
- Article
- Hematopoietic stem cell-independent and -dependent hematopoiesis: new insights and lineage-tracing methods.Experimental hematology · 2026Review
- Fitness Training for γδ T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organs.Genome medicine · 2026Article
- GFI1 as a novel regulator of γδ T cell development and the IL-17/IFN-γ lineage commitment.Frontiers in immunology · 2026Article
- Radioresistant intrathymic stem cells: retrospective analysis and concept of the role in thymic oncogenesis and post-irradiation regeneration.Frontiers in immunology · 2026Review
- Developmental hematopoiesis: innate programming of αβ T cells.Experimental hematology · 2026Review
- RasGRP1 signaling is required for Vγ2+ thymocyte c-Maf expression and γδT17 lineage programming.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Single cell transcriptomics of human psoriasis and epidermal specific Ube2l3 deficient mice highlight CXCL16/CXCR6 involvement in psoriasis development.Nature communications · 2025Article
- HEB collaborates with TCR signaling to upregulatebioRxiv : the preprint server for biology · 2025Article
- Partial Compensation of IL-17 Production by Vγ1 T Cells in the Absence of Vγ4 and Vγ6 T Cells.European journal of immunology · 2025Article
- Single-cell analysis of pig lung leukocytes and their response to influenza infection and oseltamivir therapy.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Signature cytokine-associated transcriptome analysis of effector γδ T cells identifies subset-specific regulators of peripheral activation.Nature immunology · 2025Article
- RORγt inverse agonists demonstrating a margin between inhibition of IL-17A and thymocyte apoptosis.PloS one · 2025Article
- The TCR and LCK: foundations for T-cell activation and therapeutic innovation.Frontiers in immunology · 2025Review
- Article
- SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire.bioRxiv : the preprint server for biology · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 10 institutions in 4 countries.
Nicholas A SpidaleDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA, 02135, USA.
Katelyn SylviaDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA, 02135, USA.
Kavitha NarayanDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA, 02135, USA.
Bing MiuDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA, 02135, USA.
Michela FrascoliDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA, 02135, USA.
Heather J MelicharImmuno-Oncology Research Axis, Centre de recherche de Hôpital Maisonneuve-Rosemont, Montreal, QC, H1T 2M4, Canada.
Wu ZhihaoSchool of Biological Sciences, Division of Genomics and Genetics, Nanyang Technological University, SBS-04n-23, 60 Nanyang Drive, Singapore 637551.
Jan KisielowDepartment of Biology, ETH Zurich, Inst. f. Molecular Health Sciences, Zurich, Zurich, 8093, Switzerland.
Amy PalinNational Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD, 20892, USA.
Thomas SerwoldSection on Immunobiology, Joslin Diabetes Center, Harvard Medical School, Boston, MA, 02215, USA.
Paul LoveNational Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD, 20892, USA.
Michihiro KobayashiInstitute for Molecular Medicine - Stem Cell Research, University of Texas Health Sciences Center, McGovern Medical School, Houston, TX, 77030, USA.
Momoko YoshimotoInstitute for Molecular Medicine - Stem Cell Research, University of Texas Health Sciences Center, McGovern Medical School, Houston, TX, 77030, USA.
Nitya JainDepartment of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA; Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Charlestown, MA, 02129, USA.
Joonsoo KangDepartment of Pathology, University of Massachusetts Medical School, Worcester, MA, 02135, USA. Electronic address: joonsoo.kang@umassmed.edu.
University of Massachusetts Chan Medical School · USETH Zurich · CHEunice Kennedy Shriver National Institute of Child Health and Human Development · USHarvard University · USHôpital Maisonneuve-Rosemont · CAInstitute for Molecular Medicine · USMassachusetts General Hospital · USNanyang Technological University · SGNational Institutes of Health · USThe University of Texas Health Science Center at Houston · US
Funding
Genes and signals controlling mammalian hematopoiesis.ZIAHD001803 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI LOVE, PAUL E · 2009 to 2025
$36.9MInterplay of Regulatory Innate T Cells and Pathogenic T Clonotypes In DermatitisR01AR071269 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HUSEBY, ERIC S, KANG, JOONSOO · 2017 to 2021
$2.9MGene circuits programming IL-17 production in innate lymphocytesR01AI101301 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KANG, JOONSOO · 2013 to 2017
$2.1MEmbryonic origin and self-renewal of B-1a cellsR01AI121197 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YOSHIMOTO, MOMOKO · 2016 to 2020
$1.9MRegulation of T cell development by SOX13R01CA100382 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KANG, JOONSOO · 2005 to 2009
$1.5MNCI NIH HHS R01 CA100382NIAID NIH HHS R01 AI101301NIAID NIH HHS R01 AI121197NIAMS NIH HHS R01 AR071269
Abstract
Lineage-committed αβ and γδ T cells are thought to originate from common intrathymic multipotent progenitors following instructive T cell receptor (TCR) signals. A subset of lymph node and mucosal Vγ2
Indexed as
Signal TransductionAnimalsAutoantigensBiomarkersGene Expression ProfilingGene Regulatory NetworksHumansImmunophenotypingInterleukin-17MiceMice, KnockoutMice, TransgenicReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesT-Lymphocyte SubsetsTranscriptomeAutoantigensBiomarkersInterleukin-17Receptors, Antigen, T-Cell, gamma-deltaSox13 protein, mousedevelopmentIL-17SOX13T cell receptorT cellsthymustranscription factor
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.