Evidence map›Paper›PMID 30413107›Full record

ArticleJournal of clinical medicine2018

Prediction of Acute Kidney Injury after Liver Transplantation: Machine Learning Approaches vs. Logistic Regression Model.

Hyung-Chul Lee, Soo Bin Yoon, Seong-Mi Yang, Won Ho Kim, Ho-Geol Ryu, Chul-Woo Jung, Kyung-Suk Suh, Kook Hyun Lee

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Machine learning for endoscopic third ventriculostomy success prediction-a systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyung-Chul LeeDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. azong@hanmail.net.
Soo Bin YoonDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. yunsb0107@gmail.com.
Seong-Mi YangDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. seongmi.yang@gmail.com.
Won Ho KimDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. wonhokim@snu.ac.kr.ORCID 0000-0003-1748-1296
Ho-Geol RyuDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. hogeol@gmail.com.
Chul-Woo JungDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. jungcwoo@gmail.com.
Kyung-Suk SuhDepartment of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 03080, Korea. kssuh@snu.ac.kr.
Kook Hyun LeeDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 03080, Korea. leekh@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) after liver transplantation has been reported to be associated with increased mortality. Recently, machine learning approaches were reported to have better predictive ability than the classic statistical analysis. We compared the performance of machine learning approaches with that of logistic regression analysis to predict AKI after liver transplantation. We reviewed 1211 patients and preoperative and intraoperative anesthesia and surgery-related variables were obtained. The primary outcome was postoperative AKI defined by acute kidney injury network criteria. The following machine learning techniques were used: decision tree, random forest, gradient boosting machine, support vector machine, naïve Bayes, multilayer perceptron, and deep belief networks. These techniques were compared with logistic regression analysis regarding the area under the receiver-operating characteristic curve (AUROC). AKI developed in 365 patients (30.1%). The performance in terms of AUROC was best in gradient boosting machine among all analyses to predict AKI of all stages (0.90, 95% confidence interval [CI] 0.86⁻0.93) or stage 2 or 3 AKI. The AUROC of logistic regression analysis was 0.61 (95% CI 0.56⁻0.66). Decision tree and random forest techniques showed moderate performance (AUROC 0.86 and 0.85, respectively). The AUROC of support the vector machine, naïve Bayes, neural network, and deep belief network was smaller than that of the other models. In our comparison of seven machine learning approaches with logistic regression analysis, the gradient boosting machine showed the best performance with the highest AUROC. An internet-based risk estimator was developed based on our model of gradient boosting. However, prospective studies are required to validate our results.

Indexed as

acute kidney injuryliver transplantationmachine learning

Identifiers

PMID30413107
PMCPMC6262324

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.