Evidence map›Paper›PMID 30413024›Full record

ReviewMolecules (Basel, Switzerland)2018

Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on

Ashok Aspatwar, Jean-Yves Winum, Fabrizio Carta, Claudiu T Supuran, Milka Hammaren, Mataleena Parikka, Seppo Parkkila

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Computational and Experimental Characterization ofBioinformatics and biology insights · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. International journal of molecular sciences · 2023
    Article
  8. Article
  9. Medicinal Plants as Therapeutic Alternatives to CombatAntibiotics (Basel, Switzerland) · 2023
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Selective Inhibition ofInternational journal of molecular sciences · 2021
    Article
  16. Review
  17. Journal of enzyme inhibition and medicinal chemistry · 2020
    Article
  18. International journal of molecular sciences · 2019
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ashok AspatwarFaculty of Medicine and Health Technology, University of Tampere, 33014 Tampere, Finland. ashok.aspatwar@staff.uta.fi.ORCID 0000-0002-6938-7835
Jean-Yves WinumInstitut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM, Université de Montpellier, 34296 Montpellier CEDEX 05, France. Jean-yves.winum@umontpellier.fr.ORCID 0000-0003-3197-3414
Fabrizio CartaNeurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, 50019 Sesto Fiorentino (Firenze), Italy. fabrizio.carta@unifi.it.ORCID 0000-0002-1141-6146
Claudiu T SupuranNeurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, 50019 Sesto Fiorentino (Firenze), Italy. claudiu.supuran@unifi.it.ORCID 0000-0003-4262-0323
Milka HammarenFaculty of Medicine and Health Technology, University of Tampere, 33014 Tampere, Finland. milka.hammaren@staff.uta.fi.ORCID 0000-0001-9076-8782
Mataleena ParikkaFaculty of Medicine and Health Technology, University of Tampere, 33014 Tampere, Finland. mataleena.parikka@staff.uta.fi.
Seppo ParkkilaFaculty of Medicine and Health Technology, University of Tampere, 33014 Tampere, Finland. seppo.parkkila@staff.uta.fi.ORCID 0000-0001-7323-8536
Tampere University · FITampere University Hospital · FIUniversity of Florence · ITÉcole Nationale Supérieure de Chimie de Montpellier · FR

Funding

Jane ja Aatos Erkon Säätiö NoneSuomen Kulttuurirahasto NoneTampereen Tuberkuloosisäätiö None
6 · The paper itself

Abstract

Mycobacteria cause a variety of diseases, such as tuberculosis, leprosy, and opportunistic diseases in immunocompromised people. The treatment of these diseases is problematic, necessitating the development of novel treatment strategies. Recently, β-carbonic anhydrases (β-CAs) have emerged as potential drug targets in mycobacteria. The genomes of mycobacteria encode for three β-CAs that have been cloned and characterized from

Indexed as

Antitubercular AgentsBacterial ProteinsBiofilmsCarbonic Anhydrase ICarbonic Anhydrase InhibitorsModels, MolecularMycobacterium tuberculosisStructure-Activity RelationshipVirulenceAntitubercular AgentsBacterial ProteinsCarbonic Anhydrase ICarbonic Anhydrase Inhibitorscarbonic anhydrase inhibitorsdrug targetsin vitro inhibitionin vivo inhibitionmycobacterial diseasesMycobacterium tuberculosisβ-carbonic anhydrases

Identifiers

PMID30413024
PMCPMC6278287
OpenAlexW2899842177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.