Evidence map›Paper›PMID 30413008›Full record

ArticleMolecules (Basel, Switzerland)2018

Antiproliferative Activity of Combined Biochanin A and Ginsenoside Rh₂ on MDA-MB-231 and MCF-7 Human Breast Cancer Cells.

Guixing Ren, Zhenxing Shi, Cong Teng, Yang Yao

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Biomolecules · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guixing RenCollege of Pharmacy and Biological Engineering, Chengdu University, No.1 Shilling Road, Chenglo Avenue, Longquan District, Chengdu 610106, China. guixin@126.com.
Zhenxing ShiLaboratory of Biomass and Green Technologies, University of Liege-Gembloux Agro-Bio Tech, Passage des Déportés 2, B-5030 Gembloux, Belgium. zhenxing@126.com.
Cong TengInstitute of Crop Science, Chinese Academy of Agricultural Sciences, No.80 South Xueyuan Road, Haidian District, Beijing 100081, China. 82101172124@caas.cn.
Yang YaoInstitute of Crop Science, Chinese Academy of Agricultural Sciences, No.80 South Xueyuan Road, Haidian District, Beijing 100081, China. yaoyang@caas.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most frequently diagnosed cancer in women worldwide. The antiproliferative activities of biochanin A (BA) and ginsenoside Rh₂ were determined by evaluating their inhibitory effect on MDA-MB-231 human breast cancer cell proliferation. The combination of BA with Rh₂ was also assessed. In MDA cells, combination treatment led to a decrease in the EC

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsCell Line, TumorCell MovementCell ProliferationCell SurvivalDrug SynergismFemaleGene Expression Regulation, NeoplasticGenisteinGinsenosidesHumansMAP Kinase Kinase Kinase 5MCF-7 Cellsp38 Mitogen-Activated Protein KinasesPhosphorylationbiochanin AGenisteinginsenoside Rh2GinsenosidesMAP3K5 protein, humanMAP Kinase Kinase Kinase 5p38 Mitogen-Activated Protein KinasesPSMD2 protein, humanTNF Receptor-Associated Factor 2TP53 protein, humanTumor Suppressor Protein p53antiproliferative activitybiochanin Abreast cancerRh2synergy

Identifiers

PMID30413008
PMCPMC6278524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.