Trial reportPloS one2018
Declines in exercise performance are prevented 24 hours after post-exercise ischemic conditioning in amateur cyclists.
Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ischemia-Reperfusion Intervention: From Enhancements in Exercise Performance to Accelerated Performance Recovery-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Acute effects of ischemic preconditioning on maximal strength and neuromuscular function.European journal of applied physiology · 2026Trial
- Trial
- Acute Photobiomodulation Does Not Influence Specific High-Intensity and Intermittent Performance in Female Futsal Players.International journal of environmental research and public health · 2020Trial
- Ischemic preconditioning has no effect on maximal arm cycling exercise in women.European journal of applied physiology · 2020Trial
- Accelerating an Olympic Decathlete's Return to Competition Using High-Frequency Blood Flow Restriction Training: A Case Report.Sports (Basel, Switzerland) · 2025Article
- Potential Short- and Long-Term Physiological Effects of Ischemic Preconditioning as an Ergogenic Aid: Revisiting Foundational Mechanisms and Applications.Sports medicine (Auckland, N.Z.) · 2025Review
- Blood Flow Restriction Training: A Tool to Enhance Rehabilitation and Build Athlete Resiliency.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- The effects of different ischemic conditioning on strength training recovery.Biology of sport · 2025Article
- Evaluating Local Muscle Oxygen Saturation: Ischemic Preconditioning Protocols and the Myth of Overcompensation.Journal of human kinetics · 2025Article
- Blood flow restriction as a post-exercise recovery strategy: A systematic review of the current status of the literature.Biology of sport · 2024Review
- Current Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes.Nutrients · 2024Review
- Ischemic preconditioning and exercise performance: are the psychophysiological responses underestimated?European journal of applied physiology · 2023Review
- Ischemic Preconditioning Improves the Bench-Press Maximal Strength in Resistance-Trained Men.International journal of exercise science · 2023Article
- The Acute Effects of Ischemic Preconditioning on Short-Duration Cycling: A Randomized Crossover Study.International journal of exercise science · 2023Article
- Editorial: Ergogenic Aids: Physiological and Performance Responses.Frontiers in sports and active living · 2022Article
- Potential physiological responses contributing to the ergogenic effects of acute ischemic preconditioning during exercise: A narrative review.Frontiers in physiology · 2022Review
- Blood Flow Restriction: Cause for Optimism, But Let's Not Abandon The Fundamentals.International journal of sports physical therapy · 2021Article
- Methodological Variations Contributing to Heterogenous Ergogenic Responses to Ischemic Preconditioning.Frontiers in physiology · 2021Review
- Time Course of Recovery for Performance Attributes and Circulating Markers of Muscle Damage Following a Rugby Union Match in Amateur Athletes.Sports (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brief moments of blood flow occlusion followed by reperfusion may promote enhancements in exercise performance. Thus, this study assessed the 24-h effect of post-exercise ischemic conditioning (PEIC) on exercise performance and physiological variables in trained cyclists. In a randomized, single-blind study, 28 trained cyclists (27.1 ± 1.4 years) performed a maximal incremental cycling test (MICT). The outcome measures were creatine kinase (CK), muscle soreness and perceived recovery status, heart rate, perceived exertion and power output. Immediately after the MICT, the cyclists performed 1 of the following 4 interventions: 2 sessions of 5-min occlusion/5-min reperfusion (PEIC or SHAM, 2 x 5) or 5 sessions of 2-min occlusion/2-min reperfusion (PEIC or SHAM, 5 x 2). The PEIC (50 mm Hg above the systolic blood pressure) or SHAM (20 mm Hg) treatment was applied unilaterally on alternating thighs. At 24 h after the interventions, a second MICT was performed. In all the groups, the CK levels were increased compared with the baseline (p < 0.05) after the 24-h MICT. The PEIC groups (2 x 5 and 5 x 2) felt more tired at 24 h post intervention (p < 0.05). However, both PEIC groups maintained their performance (2 x 5: p = 0.819; 5 x 2: p = 0.790), while the SHAM groups exhibited decreased performance at 24 h post intervention compared to baseline (2 x 5: p = 0.015; 5 x 2: p = 0.045). A decrease in the maximal heart rate (HR) was found only in the SHAM 2 x 5 group (p = 0.015). There were no other significant differences in the heart rate, power output or perceived exertion after 24 h compared with the baseline values for any of the interventions (p > 0.05). In conclusion, PEIC led to maintained exercise performance 24 h post intervention in trained cyclists.
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