Evidence map›Paper›PMID 30412128›Full record

ArticleMedicine2018

Natural prognosis of carbapenem-resistant Acinetobacter baumannii bacteremia in patients who did not receive appropriate antibiotic treatment: A retrospective multicenter study in Korea.

Tark Kim, Eun Jung Lee, Seong Yeon Park, Shi Nae Yu, Yu Mi Lee, Ki-Ho Park, Se Yoon Park, Min Hyok Jeon, Eun Ju Choo, Tae Hyong Kim and 1 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Turning the Tide Against Carbapenem-resistantOpen forum infectious diseases · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Clinical Characteristics and Prognosis Analysis ofInfection and drug resistance · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Review
  17. Colistin, Hot Potato for the Therapy of Carbapenem-resistantJournal of Korean medical science · 2019
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Tark KimDepartment of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon.
Eun Jung LeeDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul.
Seong Yeon ParkDepartment of Internal Medicine, Dongguk University Ilsan Hospital, Ilsan.
Shi Nae YuDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan.
Yu Mi LeeDepartment of Internal Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.
Ki-Ho ParkDepartment of Internal Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.
Se Yoon ParkDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul.
Min Hyok JeonDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan.
Eun Ju ChooDepartment of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon.
Tae Hyong KimDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul.
Mi Suk LeeDepartment of Internal Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.
Kyung Hee University Dental Hospital · KRSoonchunhyang University · KRSoonchunhyang University Hospital Seoul · KRBucheon University · KRDongguk University Ilsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenem-resistant Acinetobacter baumannii (CRAB) infection is a major issues in current era. The aim of study was to investigate the natural prognosis and prognostic factors associated with 28-day mortality in patients with CRAB bacteremia who were not receiving appropriate antibiotic treatment.Adult patients with CRAB bacteremia were retrospectively identified between April 2012 and March 2015 at 5 tertiary hospitals in Republic of Korea. Patients who were transferred to another hospital within 28 days of onset of bacteremia and who receive appropriate antibiotics more than 48 hours were excluded. We investigated prognostic factors associated with 28-day mortality in patients with CRAB bacteremia without appropriate antibiotic treatment.Of enrolled 205 patients, 143 (69.8%) patients died within 28 days after blood culture. Of patients with 28-day mortality, 88.9% (127/143) of patients died within 5 days. Of 78 patients who survived more than 5 days, the 28-day mortality was 20.5% (16/78). Diabetes mellitus (adjusted odds ratio [aOR] 3.81, 95% confidence interval [95% CI] 1.19-12.20), immunocompromised (aOR 8.72, 95% CI 2.62-29.70), sequential organ failure assessment (SOFA) ≥ 10 (aOR 13.87, 95% CI 3.70-51.96), vasopressor use (aOR 7.03, 95% CI 1.79-27.60), and pneumonia (aOR 4.44, 95% CI 1.67-11.78) were found to be the factors independently associated with the 28-day mortality.The 28-day mortality in patients with CRAB bacteremia without appropriate treatment was high, although some patients could survive. Severity and underlying conditions were important prognostic factors in patients with CRAB bacteremia.

Indexed as

Acinetobacter baumanniibeta-Lactam ResistanceAcinetobacter InfectionsAgedAnti-Bacterial AgentsCarbapenemsFemaleHumansMaleMiddle AgedPrognosisRepublic of KoreaRetrospective StudiesAnti-Bacterial AgentsCarbapenems

Identifiers

PMID30412128
PMCPMC6221697
OpenAlexW2898445129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.