Observational studyMedicine2018
Association of lymphocyte to monocyte ratio with severity of coronary artery disease.
Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Importance of so called "novel cardiovascular risk factors" in severity of coronary artery calcification; how serious they should be taken: a systematic review and metaanalysis.Archivos de cardiologia de Mexico · 2023Pooled it
- Consumption of Different Egg-Based Diets Alters Clinical Metabolic and Hematological Parameters in Young, Healthy Men and Women.Nutrients · 2023Trial
- Baseline neutrophil-to-lymphocyte ratio and efficacy of SGLT2 inhibition with empagliflozin on cardiac remodelling.ESC heart failure · 2023Trial
- Ejection fraction and absolute delta troponin in the early emergency department assessment of high coronary disease burden in NSTEMI patients: a retrospective observational study.BMC emergency medicine · 2026Observational
- Coronary slow flow: role of systemic inflammation and biomarkers in its pathophysiology.BMC cardiovascular disorders · 2026Article
- Associations of Inflammatory Markers and Coronary Heart Disease in Different Gender Groups in Cohort NHANES 2003-2018.Cardiology research and practice · 2026Article
- Lymphocyte-to-monocyte ratio is associated with all‑cause and cardiovascular mortality among individuals with diabetes mellitus in the National Health and Nutrition Examination Survey 2003-2018 cohort.BMC cardiovascular disorders · 2025Article
- Lipoprotein(a) and Blood Monocytes as Factors for Progression of Carotid Atherosclerosis in Patients with Premature Coronary Heart Disease.Diseases (Basel, Switzerland) · 2025Article
- Mutual Effect of Nutritional Status and Inflammatory Processon Mortality after Superficial Artery Intervention: NAPLES Score.Acta Cardiologica Sinica · 2025Article
- A Visualized Nomogram to Predict the Risk of Acute Ischemic Stroke Among Patients With Cervical Artery Dissection.International journal of general medicine · 2025Article
- The predictive value of serum MHR combined with classical metabolic syndrome components in the first trimester for gestational metabolic syndrome: a prospective cohort study in China.Frontiers in medicine · 2025Article
- Lymphocyte-to-Monocyte Ratio and All-Cause Mortality in Populations With Abdominal Aortic Calcification: A Prospective Cohort Study.Mediators of inflammation · 2025Article
- Relationship Between Inflammatory Readings and the Degree of Coronary Atherosclerosis (Pilot Study).Journal of clinical medicine · 2024Article
- Evaluating SORT1 and SESN1 genes expression in peripheral blood mononuclear cells and oxidative stress status in patients with coronary artery disease.BMC genomic data · 2024Article
- Inflammation indices in association with periodontitis and cancer.Periodontology 2000 · 2024Review
- Role of lymphocyte-to-monocyte ratio as a predictive marker for diabetic coronary artery disease: A cross-sectional study.World journal of methodology · 2024Article
- Article
- Association of systemic inflammatory indices with anthropometric measures, metabolic factors, and liver function in non-alcoholic fatty liver disease.Scientific reports · 2024Article
- Novel Systemic Inflammatory Markers Predict All-Cause Mortality in Patients Undergoing Endovascular Abdominal Aortic Aneurysm Repair.Reviews in cardiovascular medicine · 2024Article
- Synovial fluid monocyte-to-lymphocyte ratio in knee osteoarthritis patients predicts patient response to conservative treatment: a retrospective cohort study.BMC musculoskeletal disorders · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the relationship between lymphocyte to monocyte ratio (LMR) and the severity of coronary artery disease (CAD) by using Gensini score.A total of 199 patients, who had undergone coronary angiography, were included in the study and retrospectively analyzed. Among them, 49 patients who had normal coronary arteries were selected as the control group. Patients with CAD were divided into 2 groups, those with low Gensini score (≤40) and those with high Gensini score (≥40).Our results showed that LMR in the severe atherosclerosis group was significantly lower than those of the mild atherosclerosis group and the control group. There was a closely significant correlation between the Gensini score and LMR (r = -0.362, P < .001). Furthermore, multivariate logistic regression analysis demonstrated that LMR (odds ratio, 0.715; 95% confidence interval [CI], 0.551-0.927; P = .012) was independent predictors of severe atherosclerosis. Using an optimal LMR cut-off value of 5.06, LMR predicted severe atherosclerosis with a sensitivity of 57.1% and specificity of 69.7% (area under curve = 0.634; 95% CI, 0.545-0.724; P = .005). Then patients with CAD group was divided into 2 groups according to the LMR value of 5.06. Patients with LMR ≤ 5.06 had worse prognosis, with a higher rate of cardiovascular events during up to 1 year follow-up.Our study demonstrated that LMR was independently and positively associated with the severity of coronary atherosclerosis, providing a new insight in the application of inflammation index evaluating the severity of CAD. And LMR may be a useful predictor of future cardiovascular events in patients with CAD.
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