Evidence map›Paper›PMID 30412035›Full record

ArticleTissue engineering. Part C, Methods2018

Stabilization and Sterilization of Pericardial Scaffolds by Ultraviolet and Low-Energy Electron Irradiation.

Simona Walker, Jessy Schönfelder, Sems-Malte Tugtekin, Christiane Wetzel, Michael C Hacker, Michaela Schulz-Siegmund

Open access · hybridAbstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Simona Walker1 Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, Dresden, Germany.
Jessy Schönfelder1 Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, Dresden, Germany.
Sems-Malte Tugtekin2 Department of Cardiac Surgery, Faculty of Medicine CGC, Technische Universität Dresden, Herzzentrum Dresden, Dresden, Germany.
Christiane Wetzel1 Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, Dresden, Germany.
Michael C Hacker3 Institute of Pharmacy, Pharmaceutical Technology, Faculty of Medicine, Leipzig University, Leipzig, Germany.
Michaela Schulz-Siegmund3 Institute of Pharmacy, Pharmaceutical Technology, Faculty of Medicine, Leipzig University, Leipzig, Germany.
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology · DELeipzig University · DETechnische Universität Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impact statementPericardium-based tissue transplantation is a lifesaving treatment. Commercial glutaraldehyde-treated pericardial tissue exhibits cytotoxicity, which is associated with the accelerated graft failure. Replacement of glutaraldehyde has been suggested to overcome those drawbacks. In this study, we report a toxin-free method that combines tissue stabilization with a terminal sterilization. Our data indicate that the SULEEI procedure, which is part of an issued patent, may be a promising first step toward glutaraldehyde-free pericardium-based tissue transplants. Thus, our results may contribute to improving cardiovascular treatment strategies.

Indexed as

ElectronsUltraviolet RaysAnimalsCell DeathComputer SimulationDNAHumansHuman Umbilical Vein Endothelial CellsPericardiumSterilizationSwineTissue ScaffoldsDNAglutaraldehydeionizing irradiationlow-energy electron irradiationpericardiumsterilizationSULEEI

Identifiers

PMID30412035
PMCPMC6306682
OpenAlexW2900171522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.