ArticleJournal of clinical laboratory analysis2019
Early prediction of severity in acute ischemic stroke and transient ischemic attack using platelet parameters and neutrophil-to-lymphocyte ratio.
Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Stroke: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Clinical Significance of Baseline Neutrophil-to-Lymphocyte Ratio in Patients With Ischemic Stroke or Hemorrhagic Stroke: An Updated Meta-Analysis.Frontiers in neurology · 2019Pooled it
- Correlation of composite inflammatory indices and homocysteine with the severity of acute ischemic stroke: A retrospective study.Medicine · 2026Article
- Study on the non-linear relationship between neutrophil-to-lymphocyte ratio and prognosis of spontaneous intraventricular hemorrhage.Frontiers in neurology · 2025Article
- Serial Examination of Platelet Function Tests Might Predict Prognosis of Patients with Acute Ischemic Stroke-A Cohort Study.Diagnostics (Basel, Switzerland) · 2024Article
- The Aggregate Index of Systemic Inflammation as a Predictor of Mortality in Stroke Patients.Cureus · 2024Article
- Evaluation of Hemoglobin and Eosinophil Count in Patients Receiving Thrombolytic Treatment.Cureus · 2024Article
- Effects of peripheral blood cells on ischemic stroke: Greater immune response or systemic inflammation?Heliyon · 2024Review
- Neutrophil-to-lymphocyte ratio as a predictor for cardiovascular diseases: a cohort study in Tianjin, China.Journal of human hypertension · 2023Article
- Blood Neutrophil-to-Lymphocyte Ratio as a Predictor of Cerebral Small-Vessel Disease.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Correlation of Immune-Inflammatory Markers with Clinical Features and Novel Location-Specific Nomograms for Short-Term Outcomes in Patients with Intracerebral Hemorrhage.Diagnostics (Basel, Switzerland) · 2022Article
- Comparison of Clinical Features, Immune-Inflammatory Markers, and Outcomes Between Patients with Acute In-Hospital and Out-of-Hospital Ischemic Stroke.Journal of inflammation research · 2022Article
- Influence of neutrophil-to-lymphocyte ratio and mean platelet volume on severity and short-term prognosis of acute ischemic stroke.American journal of translational research · 2022Article
- Article
- Neutrophil-Related Ratios Predict the 90-Day Outcome in Acute Ischemic Stroke Patients After Intravenous Thrombolysis.Frontiers in physiology · 2021Article
- Association of a High Neutrophil-to-Lymphocyte Ratio with Hyperdense Artery Sign and Unfavorable Short-Term Outcomes in Patients with Acute Ischemic Stroke.Journal of inflammation research · 2021Article
- Acute Ischemic Stroke in COVID-19: A Case-Based Systematic Review.Frontiers in neurology · 2020Review
- The White Blood Cell Count to Mean Platelet Volume Ratio for the Prediction of Chronic Limb-Threatening Ischemia in Lower Extremity Artery Disease.Journal of clinical medicine · 2019Article
- Early prediction of severity in acute ischemic stroke and transient ischemic attack using platelet parameters and neutrophil-to-lymphocyte ratio.Journal of clinical laboratory analysis · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundIt is still not easy to predict severity promptly in patients with acute ischemic stroke (AIS) and transient ischemic attack (TIA). We investigated that platelet parameters or combinations of them could be a useful tool for early prediction of severity of AIS and TIA at admission and after 3 months.
methodsWe prospectively recruited 104 patients newly diagnosed with AIS and TIA. We investigated their neutrophil-to-lymphocyte ratio (NLR) and platelet parameters. According to the Modified Rankin Scale scores, the patients were divided into two groups.
resultsIn receiver operating characteristic (ROC) curve analyses, mean platelet volume (MPV), NLR/platelet count (PLT), MPV/PLT, MPV*NLR, and MPV*NLR/PLT showed statistically significant results in both at admission and after 3 months. Values of area under ROC curves for those tests at admission were 0.646, 0.697, 0.664, 0.708, and 0.722, respectively. Also, values after 3 months were 0.591, 0.661, 0.638, 0.662, and 0.689, respectively.
conclusionMPV*NLR/PLT could be used as a relatively good tool for predicting severity at the time of admission and after 3 months than other parameters or combinations of them. Further studies have to be carried out to investigate the best parameter for predicting the severity of AIS and TIA.
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