ArticleInternational journal of rheumatic diseases2019
Clinical features and potential relevant factors of renal involvement in primary Sjögren's syndrome.
Article in International journal of rheumatic diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Factors Associated With Renal Involvement in Primary Sjögren's Syndrome: A Meta-Analysis.Frontiers in medicine · 2020Pooled it
- Clinical characteristics and prognosis of primary Sjögren's disease patients with hypocomplementemia: reduced C3 is independently associated with new-onset peripheral cytopenias.Clinical rheumatology · 2026Article
- Clinicopathologic Features and Prognostic Factors in Biopsy-Confirmed Renal Involvement in Primary Sjőgren Syndrome.Kidney360 · 2026Article
- Childhood-onset primary Sjögren's Syndrome presenting as nephrotic syndrome: a case report and literature review.BMC pediatrics · 2025Review
- Simultaneous Presentation of Minimal Change Disease and Tubulointerstitial Nephritis Associated with Primary Sjögren's Syndrome and Hashimoto's Thyroiditis.Internal medicine (Tokyo, Japan) · 2025Review
- Renal Involvement in Primary Sjögren's Syndrome: A Multi-centric Study From North India.Cureus · 2025Article
- The prevalence, clinical features, and long-term outcome of patients with primary Sjögren's syndrome with renal involvement.Scientific reports · 2025Article
- The spectrum and prognosis of Sjögren's syndrome with membranous nephropathy.Clinical kidney journal · 2025Article
- Case Report: A case of membranous nephropathy associated with primary Sjögren's syndrome treated with telitacicept.Frontiers in immunology · 2025Article
- Can unstimulated whole salivary flow objectively classify salivary gland secretory function in Sjögren's syndrome?Clinical rheumatology · 2024Article
- Severe Hypokalemia and Respiratory Muscle Paralysis: An Atypical Manifestation of Primary Sjögren's Syndrome.Cureus · 2024Article
- Analysis of risk factors and development of a nomogram prediction model for renal tubular acidosis in primary Sjogren syndrome patients.Arthritis research & therapy · 2024Article
- Hypocitraturia as a biomarker of renal tubular acidosis in patients with Sjögren's disease.Advances in rheumatology (London, England) · 2024Article
- Clinical features and risk factors of primary Sjögren's syndrome complicated with severe pneumonia: a case-control study.Clinical rheumatology · 2024Article
- Development of a nomogram for membranous nephropathy prediction in patients with primary Sjögren's syndrome: a 6-year retrospective study.Frontiers in immunology · 2024Article
- A Diagnostic and Therapeutic Dilemma Concerning Exostosin 1/Exostosin 2-associated Lupus-like Membranous Nephropathy with Positive Antinuclear Antibody in an Elderly Man with Various Immune Abnormalities.Internal medicine (Tokyo, Japan) · 2023Article
- Renal involvement in Sjőgren's syndrome: predictors and impact on patient outcomes.Rheumatology international · 2023Review
- Minimal Change Disease and Primary Sjogren Syndrome Concurrence: Case-Based review.European journal of rheumatology · 2022Article
- Hypocomplementemia in primary Sjogren's syndrome: association with serological, clinical features, and outcome.Clinical rheumatology · 2022Article
- Recommendations for evaluation and diagnosis of extra-glandular manifestations of primary sjogren syndrome: results of an epidemiologic systematic review/meta-analysis and a consensus guideline from the Brazilian Society of Rheumatology (articular, pulmonary and renal).Advances in rheumatology (London, England) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate distinct features of renal involvement in patients with primary Sjögren's syndrome (pSS) and to identify potential factors associated with renal involvement.
methodsFour hundred and thrity-four pSS patients from the Rheumatology Department of the First Affiliated Hospital of Wenzhou Medical University from 2013 to 2017 were included in a cross-sectional study. Patients with renal involvement were compared with their age- and gender-matched controls (pSS without renal involvement). Demographic, clinical, histological, nephritic, immunological features of renal involvement in pSS were systematically analyzed. Possible factors related to renal involvement were identified using multivariate logistic regression analyses.
resultsOne hundred and ninety-two pSS patients (88.48%) with renal involvement were women with mean age of nearly 58 years and mean disease duration of above 4 years. Clinical manifestation, serologic and immunological features and renal biopsy class of the pSS patients with renal involvement were presented. By multivariate analyses, xerophthalmia, histological positivity for lower salivary gland biopsy (LSGB), anti-SSA/Ro52-positive, reduced complement 3 (C3) levels, hypoalbuminemia and anemia retained significant association with renal involvement in pSS (all P < 0.05).
conclusionIn addition to LSGB pattern, anti-SSA/Ro52-positivity, reduced C3 levels, hypoalbuminemia and anemia, also indicate significant association with renal involvement in pSS. Therefore, early vigilance is required for patients with these clinical manifestations.
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