Evidence map›Paper›PMID 30411426›Full record

ReviewMolecular reproduction and development2019

The eggstraordinary story of how life begins.

John Parrington, Christophe Arnoult, Rafael A Fissore

Abstract readReview
In one paragraph

Review in Molecular reproduction and development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Toward the understanding of biology of oocyte life cycle inReproductive medicine and biology · 2020
    Review
  7. CaCold Spring Harbor perspectives in biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

John ParringtonDepartment of Pharmacology, University of Oxford, Oxford, UK.
Christophe ArnoultUniversité Grenoble Alpes, Grenoble, France.
Rafael A FissoreDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts.ORCID 0000-0002-8001-7632
Centre National de la Recherche Scientifique · FRUniversity of Massachusetts Amherst · USUniversity of Oxford · GB

Funding

Regulation of the functional expression of the TRPM7 chanzyme essential for Mg2+ homeostasis in mouse oocytes and cleaving embryos to improve assisted reproductive technologies and modulate fertilityR01HD092499 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Rafael Antonio Fissore · 2018 to 2026
$2.0M
LP3R-1 Regulation and Egg ActivationR01HD051872 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI FISSORE, RAFAEL ANTONIO · 2007 to 2011
$1.3M
Eunice Kennedy Shriver National Institute of Child Health and Human Development HD051872Eunice Kennedy Shriver National Institute of Child Health and Human Development HD092499NICHD NIH HHS R01 HD051872NICHD NIH HHS R01 HD092499NIFA 1727
6 · The paper itself

Abstract

More than 15 years have elapsed since the identification of phospholipase C ζ1 (PLCζ) from a genomic search for mouse testis/sperm-specific PLCs. This molecule was proposed to represent the sperm factor responsible for the initiation of calcium (Ca

Indexed as

Calcium SignalingEmbryonic DevelopmentSperm-Ovum InteractionsAnimalsEmbryo, MammalianFemaleHumansInfertility, MaleMaleMicePhosphoinositide Phospholipase CSpermatozoaSperm Injections, IntracytoplasmicPhosphoinositide Phospholipase CPlcz1 protein, mousecalciumegg activationfertilizationinfertilityIP3mammalsoocytesoscillationsspermsperm factor

Identifiers

PMID30411426
PMCPMC6352315
OpenAlexW2899810827

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.