Evidence map›Paper›PMID 30411328›Full record

ArticleCancer2019

The incidence of fatal breast cancer measures the increased effectiveness of therapy in women participating in mammography screening.

László Tabár, Peter B Dean, Tony Hsiu-Hsi Chen, Amy Ming-Fang Yen, Sam Li-Sheng Chen, Jean Ching-Yuan Fann, Sherry Yueh-Hsia Chiu, May Mei-Sheng Ku, Wendy Yi-Ying Wu, Chen-Yang Hsu and 4 more

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Article in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

László TabárDepartment of Mammography, Falun Central Hospital, Falun, Sweden.
Peter B DeanDepartment of Radiology, University of Turku, Turku, Finland.
Tony Hsiu-Hsi ChenGraduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Amy Ming-Fang YenSchool of Oral Hygiene, Collage of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Sam Li-Sheng ChenSchool of Oral Hygiene, Collage of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Jean Ching-Yuan FannDepartment of Nutrition and Health Sciences, Kainan University, Taoyuan, Taiwan.
Sherry Yueh-Hsia ChiuDepartment of Health Care Management, Chang Gung University, Taoyuan, Taiwan.
May Mei-Sheng KuGraduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Wendy Yi-Ying WuDepartment of Radiation Sciences, Umeå University, Umea, Sweden.
Chen-Yang HsuGraduate Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Yu-Ching ChenDepartment of Biostatistics, Taipei City Hospital, Taipei, Taiwan.
Kerri BeckmannCenter for Population Health Research, University of South Australia, Adelaide, Australia.
Robert A SmithCancer Control Department, and Center for Quality Cancer Screening and Research, American Cancer Society, Atlanta, Georgia.
Stephen W DuffyCenter for Cancer Prevention, Queen Mary University of London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen and their health care providers need a reliable answer to this important question: If a woman chooses to participate in regular mammography screening, then how much will this choice improve her chances of avoiding a death from breast cancer compared with women who choose not to participate?

methodsTo answer this question, we used comprehensive registries for population, screening history, breast cancer incidence, and disease-specific death data in a defined population in Dalarna County, Sweden. The annual incidence of breast cancer was calculated along with the annual incidence of breast cancers that were fatal within 10 and within 11 to 20 years of diagnosis among women aged 40 to 69 years who either did or did not participate in mammography screening during a 39-year period (1977-2015). For an additional comparison, corresponding data are presented from 19 years of the prescreening period (1958-1976). All patients received stage-specific therapy according to the latest national guidelines, irrespective of the mode of detection.

resultsThe benefit for women who chose to participate in an organized breast cancer screening program was a 60% lower risk of dying from breast cancer within 10 years after diagnosis (relative risk, 0.40; 95% confidence interval, 0.34-0.48) and a 47% lower risk of dying from breast cancer within 20 years after diagnosis (relative risk, 0.53; 95% confidence interval, 0.44-0.63) compared with the corresponding risks for nonparticipants.

conclusionsAlthough all patients with breast cancer stand to benefit from advances in breast cancer therapy, the current results demonstrate that women who have participated in mammography screening obtain a significantly greater benefit from the therapy available at the time of diagnosis than do those who have not participated.

Indexed as

AdultAgedBreast NeoplasmsCombined Modality TherapyEarly Detection of CancerFemaleFollow-Up StudiesHumansIncidenceMammographyMiddle AgedPrognosisRegistriesSurvival RateSwedenbreast cancerfatalitymammographymortalityscreening

Identifiers

PMID30411328
PMCPMC6588008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.