Evidence map›Paper›PMID 30411080›Full record

ArticleHepatology communications2018

Liver Fibrosis Markers Improve Prediction of Outcome in Non-Acetaminophen-Associated Acute Liver Failure.

Aya Ugamura, Po-Sung Chu, Nobuhiro Nakamoto, Nobuhito Taniki, Keisuke Ojiro, Taizo Hibi, Masahiro Shinoda, Hideaki Obara, Yohei Masugi, Akihiro Yamaguchi and 7 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Recent Use of Hyaluronic Acid in Dental Medicine.Materials (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Aya UgamuraDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Po-Sung ChuDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.ORCID 0000-0002-8687-2760
Nobuhiro NakamotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Nobuhito TanikiDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Keisuke OjiroDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Taizo HibiDepartment of Surgery Keio University School of Medicine Tokyo Japan.
Masahiro ShinodaDepartment of Surgery Keio University School of Medicine Tokyo Japan.
Hideaki ObaraDepartment of Surgery Keio University School of Medicine Tokyo Japan.
Yohei MasugiDepartment of Pathology Keio University School of Medicine Tokyo Japan.
Akihiro YamaguchiDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Shunsuke ShibaDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Rei MorikawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Shingo UsuiDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Hirotoshi EbinumaDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Yuko KitagawaDepartment of Surgery Keio University School of Medicine Tokyo Japan.
Hidetsugu SaitoDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Takanori KanaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine Keio University School of Medicine Tokyo Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A prognostic system for acute liver failure (ALF) with a higher predictive value is urgently needed. The role of extracellular matrix (ECM) remodeling in ALF has not been fully elucidated. We hypothesized that serologic fibrosis markers, which reflect ECM remodeling, are predictive of ALF outcome at first presentation. This observational study included 110 patients with acute liver dysfunction, of which 73 had non-acetaminophen-associated ALF (NAA-ALF). We evaluated serum levels of hyaluronic acid, 7S domain of type IV collagen (4COL7S), and

Identifiers

PMID30411080
PMCPMC6211334
OpenAlexW2893335779

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.