ArticleACS omega2018
Aggregation-Enhanced Emission of Gold Nanoclusters Induced by Serum Albumin and Its Application to Protein Detection and Fabrication of Molecular Logic Gates.
Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 34 citations in OpenAlex.
- Effect of different crystal forms of MnOMikrochimica acta · 2024Article
- Fluorescence turn-on detection of human serum albumin based on the assembly of gold nanoclusters and bromocresol green.Analytical and bioanalytical chemistry · 2023Article
- Higher-order assembly of BSA gold nanoclusters using supramolecular host-guest chemistry: a 40% absolute fluorescence quantum yield.Nanoscale advances · 2022Article
- Flavin adenine dinucleotide-capped gold nanoclusters: biocompatible photo-emissive nanomaterial and reservoir of lumichrome.Nanoscale advances · 2022Article
- Development of an enhanced immunoassay based on protein nanoparticles displaying an IgG-binding domain and luciferase.Analytical and bioanalytical chemistry · 2022Article
- Post-Synthesis Modification of Photoluminescent and Electrochemiluminescent Au Nanoclusters with Dopamine.Nanomaterials (Basel, Switzerland) · 2020Article
- Facile Hydrophobication of Glutathione-Protected Gold Nanoclusters and Encapsulation into Poly(lactide-co-glycolide) Nanocarriers.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exploring aggregation-enhanced emission (AEE) of gold nanoclusters (Au NCs) is beneficial for extending their applications in sensing and molecular information processing. Herein, we present the first report of a protein-induced AEE effect of Au NCs. When human serum albumin (HSA) is mixed with glutathione-capped Au NCs under appropriate pH conditions, the Au NCs undergo extensive aggregation and exhibit significantly enhanced emission, attributed to the electrostatic and hydrophobic interactions between HSA and the NCs. Such an AEE effect is specific to serum albumin over a variety of other proteins, which facilitates the development of a facile approach for HSA determination. This sensing method displays satisfactory recoveries of 96.0-98.7% when it is applied to HSA detection in artificial urine. Moreover, the AEE effect is suited to the fabrication of AND and INHIBIT logic gates by using HSA and pH/protein-binding drug as inputs and the emission as output.
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Registered trials
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