Evidence map›Paper›PMID 30410905›Full record

ArticleSkin appendage disorders2018

Asymmetric Acral Spared Phenomenon Related to Systemic Anticancer Therapies.

Robert Baran, Caroline Robert, Vincent Sibaud

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Skin appendage disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Robert BaranNail Disease Center, Cannes, France.
Caroline RobertDepartment of Oncology and Dermatology, Gustave Roussy Institute, Villejuif, France.
Vincent SibaudDepartment of Oncodermatology, Claudius Regaud Institute, Cancer University Institute, Toulouse Oncopole, Toulouse, France.
Centre Hospitalier de Cannes · FRInstitut Claudius Regaud · FRInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have observed three patients on anticancer therapies presenting with asymmetric acral spared phenomenon and found six identical cases in the literature. All of them had common features, an alteration of the peripheral nerves affecting a limb unilaterally that was spared by a hand-foot syndrome or hand-foot skin reaction. A drug-induced neurotropic effect sounds logical for developing such alterations with specific chemotherapeutic agents (taxanes, cap-ecitabine), while we have not found good explanations concerning the multikinase inhibitor sorafenib nor the topo isomerase inhibitor adriamycin. Nevertheless, we know that clinical manifestations of many inflammatory diseases need intact neural components.

Indexed as

Anticancer therapiesAnticox 2Hand-foot syndromeOnycholysisReaction sparing a limb unilaterallyTaxanesUnilateral acral changes

Identifiers

PMID30410905
PMCPMC6219227
OpenAlexW2789632185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.