Evidence map›Paper›PMID 30410684›Full record

ArticleNano research2018

General synthesis of silica-based yolk/shell hybrid nanomaterials and

Feng Chen, Shreya Goel, Sixiang Shi, Todd E Barnhart, Xiaoli Lan, Weibo Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Nanomedicine in cancer therapy.Signal transduction and targeted therapy · 2023
    Review
  3. Review
  4. Article
  5. Silica Nanoparticles.Advances in experimental medicine and biology · 2021
    Article
  6. Mesoporous Silica Nanoparticles as Carriers for Biomolecules in Cancer Therapy.Advances in experimental medicine and biology · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Feng ChenDepartment of Radiology, University of Wisconsin-Madison, WI 53705, USA.
Shreya GoelMaterials Science Program, University of Wisconsin-Madison, WI 53705, USA.
Sixiang ShiMaterials Science Program, University of Wisconsin-Madison, WI 53705, USA.
Todd E BarnhartDepartment of Medical Physics, University of Wisconsin-Madison, WI 53705, USA.
Xiaoli LanDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Weibo CaiDepartment of Radiology, University of Wisconsin-Madison, WI 53705, USA.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Novel Combination Therapy for Prostate CancerR01CA169365 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CAI, WEIBO · 2013 to 2015
$903k
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA169365
6 · The paper itself

Abstract

Multifunctional yolk/shell-structured hybrid nanomaterials have attracted increasing interest as theranostic nanoplatforms for cancer imaging and therapy. However, because of the lack of suitable surface engineering and tumor targeting strategies, previous research has focused mainly on nanostructure design and synthesis with few successful examples showing active tumor targeting after systemic administration. In this study, we report the general synthetic strategy of chelator-free zirconium-89 (

Indexed as

intrinsic radiolabelingpositron emission tomographyvasculature targetingyolk/shellzirconium-89

Identifiers

PMID30410684
PMCPMC6217832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.