Evidence map›Paper›PMID 30410581›Full record

ArticleBioData mining2018

A fast forward 3D connection algorithm for mitochondria and synapse segmentations from serial EM images.

Weifu Li, Jing Liu, Chi Xiao, Hao Deng, Qiwei Xie, Hua Han

Abstract read
In one paragraph

Article in BioData mining, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weifu Li1Faculty of Mathematics and Statistics, Hubei University, 368 Youyi Road, Wuhan, 430062 China.
Jing Liu2Institute of Automation, Chinese Academy of Sciences, 95 Zhongguancun East Road, Beijing, 100190 China.
Chi Xiao2Institute of Automation, Chinese Academy of Sciences, 95 Zhongguancun East Road, Beijing, 100190 China.
Hao DengFaculty of Information Technology, Macau University of Science and Technology, Avenida Wai Long,Taipa, Macau, China.
Qiwei Xie4Data Mining Lab, Beijing University of Technology, 100 Ping Le Yuan, Beijing, 100124 China.
Hua Han2Institute of Automation, Chinese Academy of Sciences, 95 Zhongguancun East Road, Beijing, 100190 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is becoming increasingly clear that the quantification of mitochondria and synapses is of great significance to understand the function of biological nervous systems. Electron microscopy (EM), with the necessary resolution in three directions, is the only available imaging method to look closely into these issues. Therefore, estimating the number of mitochondria and synapses from the serial EM images is coming into prominence. Since previous studies have achieved preferable 2D segmentation performance, it holds great promise to obtain the 3D connection relationship from the 2D segmentation results.

resultsIn this paper, we improve upon Matlab's function

conclusionsThe proposed method can be deemed as an effective strategy to obtain the 3D connection relationship from serial mitochondria and synapse segmentations. It is helpful to accurately and quickly quantify the statistics of the numbers, volumes, surface areas, and lengths, which will greatly facilitate the data analysis of neurobiology research.

Indexed as

3D connectionBwconncompEM imagesMitochondriaSynapse

Identifiers

PMID30410581
PMCPMC6217761

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.