Evidence map›Paper›PMID 30410488›Full record

ArticleFrontiers in immunology2018

Frequency of Circulating CD4

Selena Ferrian, Melinda Ross, Francesca Conradie, Shaheed Vally Omar, Nazir Ismail, Francesca Little, Gilla Kaplan, Dorothy Fallows, Clive M Gray

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Emerging patterns of regulatory T cell function in tuberculosis.Clinical and experimental immunology · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Selena FerrianDivision of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Melinda RossDepartment of Statistical Sciences, University of Cape Town, Cape Town, South Africa.
Francesca ConradieFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Shaheed Vally OmarCentre for Tuberculosis, National Institute of Communicable Diseases, Johannesburg, South Africa.
Nazir IsmailCentre for Tuberculosis, National Institute of Communicable Diseases, Johannesburg, South Africa.
Francesca LittleDepartment of Statistical Sciences, University of Cape Town, Cape Town, South Africa.
Gilla KaplanPublic Health Research Institute, Rutgers University, Newark, NJ, United States.
Dorothy FallowsPublic Health Research Institute, Rutgers University, Newark, NJ, United States.
Clive M GrayDivision of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
University of Cape Town · ZARutgers, The State University of New Jersey · USNational Health Laboratory Service · ZAUniversity of Pretoria · ZAUniversity of the Witwatersrand · ZA

Funding

Emerging XDR-TB: Host and Pathogen ContributionsR01AI080737 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI FALLOWS, DOROTHY A. · 2009 to 2013
$2.9M
Analysis of XDR-TB and MDR-TB strains: safety, diagnosis and pathogenesisD43TW008264 · FIC · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2009 to 2013
$741k
FIC NIH HHS D43 TW008264NIAID NIH HHS R01 AI080737
6 · The paper itself

Abstract

Identifying a blood circulating cellular biomarker that can be used to assess severity of disease and predict the time to culture conversion (TCC) in patients with multidrug resistant tuberculosis (MDR-TB) would facilitate monitoring response to treatment and may be of value in the design of future drug trials. We report on the frequency of blood Ki67

Indexed as

Lymphocyte CountAntitubercular AgentsFemaleHLA-DR AntigensHumansImmunologic MemoryKi-67 AntigenMaleMicrobial Sensitivity TestsMycobacterium tuberculosisROC CurveSeverity of Illness IndexT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsTuberculosis, Multidrug-ResistantAntitubercular AgentsHLA-DR AntigensKi-67 Antigenculture conversionlung cavitiesmulti-drug resistant tuberculosisMycobacteria tuberculosissmear gradessputum cultureTreg cells

Identifiers

PMID30410488
PMCPMC6209685
OpenAlexW2898528026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.