Evidence map›Paper›PMID 30410487›Full record

ArticleFrontiers in immunology2018

Vaginal Lactobacilli Induce Differentiation of Monocytic Precursors Toward Langerhans-like Cells:

Jie Song, Fengchao Lang, Na Zhao, Yan Guo, Huatang Zhang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Frontiers in microbiology · 2024
    Article
  7. Review
  8. Review
  9. Vaginal Dysbiotic Microbiome in Women With No Symptoms of Genital Infections.Frontiers in cellular and infection microbiology · 2021
    Article
  10. Review
  11. Review
  12. Article
  13. Development of an Antigen Delivery Platform UsingFrontiers in microbiology · 2020
    Article
  14. Article
  15. Local ProbioticFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie SongYunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medical Science and Peking Union Medical College, Kunming, China.
Fengchao LangKey Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Na ZhaoKey Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Yan GuoKey Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Huatang ZhangChongqing Center for Biomedical Research and Equipment Development, Chongqing Academy of Science and Technology, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactobacilli have immunomodulatory mechanisms that affect the host cell immune system, leading to inhibition of HIV-1 transmission. Thus, lactobacilli as mucosal delivery vehicles for developing HIV-1 vaccines have attracted interest in recent years. Herein, we investigated the immunomodulatory effects of six strains of

Indexed as

Cell DifferentiationCell ProliferationFemaleHIV-1HIV InfectionsHumansLactobacillus crispatusLangerhans CellsLipopolysaccharide ReceptorsLymphocyte Culture Test, MixedMonocytesTHP-1 CellsT-LymphocytesVaginaVirus InternalizationLipopolysaccharide ReceptorsHIV preventionlactobacilliLangerhans-like cellmonocytic precursorspeptidoglycan

Identifiers

PMID30410487
PMCPMC6211368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.