Evidence map›Paper›PMID 30410401›Full record

ArticleCancer management and research2018

Preoperative PROSTATE scoring system: a potential predictive tool for the risk of biochemical recurrence after radical prostatectomy.

Zhe-Nan Zhang, Cheng Luo, Ben Xu, Hai-Feng Song, Bing-Lei Ma, Qian Zhang

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Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Zhe-Nan ZhangDepartment of Urology, Peking University First Hospital, Beijing 100034, People's Republic of China, zhangqianbjmu@126.com.
Cheng LuoDepartment of Urology, Peking University First Hospital, Beijing 100034, People's Republic of China, zhangqianbjmu@126.com.
Ben XuDepartment of Urology, Peking University First Hospital, Beijing 100034, People's Republic of China, zhangqianbjmu@126.com.
Hai-Feng SongDepartment of Urology, Peking University First Hospital, Beijing 100034, People's Republic of China, zhangqianbjmu@126.com.
Bing-Lei MaDepartment of Urology, Peking University First Hospital, Beijing 100034, People's Republic of China, zhangqianbjmu@126.com.
Qian ZhangDepartment of Urology, Peking University First Hospital, Beijing 100034, People's Republic of China, zhangqianbjmu@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the association between the preoperative PROSTATE scoring system and the prediction of biochemical recurrence (BCR) risk, after radical prostatectomy (RP) in prostate cancer patients. PATIENTS AND

methodsA total of 340 patients who underwent a laparoscopic radical prostatectomy in Peking University First Hospital between November 2007 and March 2016 were included in the study. The preoperative PROSTATE scoring system was measured and calculated. The performance of the scoring system to predict BCR risk was estimated using the receiver operating characteristic curve (ROC curve). BCR-free survival was analyzed using the Kaplan- Meier method, and the log-rank test was applied to compare the differences in risk among the patient groups. The Cox proportional hazards regression was used to analyze the performance of the grouped PROSTATE scores.

resultsOf the total population, 91 (26.8%) patients had BCR. The PROSTATE score was significantly different between the BCR-developed and BCR-free groups (

conclusionThe PROSTATE scoring system performed adequately in predicting the risk of BCR after RP. The scoring system can assist in decision-making about the operation and post- operative follow-up for patients with high-risk.

Indexed as

biochemical recurrencepredictivepreoperativeprostate cancerPROSTATE scoring systemradical prostatectomy

Identifiers

PMID30410401
PMCPMC6199217

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