Evidence map›Paper›PMID 30410347›Full record

ArticleOncoTargets and therapy2018

Synergistic suppression effect on tumor growth of acute myeloid leukemia by combining cytarabine with an engineered oncolytic vaccinia virus.

Jiamin Peng, Shibing Wang, Weimin Fan, Shuangshuang Li, Yi Wu, Xiaozhou Mou, Jianchao Wang, Xiangmin Tong

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jiamin PengThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China, tongxiangmin@163.com.
Shibing WangClinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China, tongxiangmin@163.com.
Weimin FanThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China, tongxiangmin@163.com.
Shuangshuang LiClinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China, tongxiangmin@163.com.
Yi WuDepartment of Hematology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
Xiaozhou MouClinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China, tongxiangmin@163.com.
Jianchao WangThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China, tongxiangmin@163.com.
Xiangmin TongThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China, tongxiangmin@163.com.
Zhejiang Chinese Medical University · CNHangzhou Medical College · CNZhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn consideration of the drug resistance and side effects associated with cytarabine, one of the most effective drugs for the treatment of acute myeloid leukemia (AML), there is a need for safer and effective strategies.

methodsIn the present investigation, we fabricated a new oncolytic vaccinia virus (oVV-

resultsThe experiments confirmed that oVV can efficiently and specifically infect leukemia cells, and augment the

conclusionIn brief, oVV-

Indexed as

acute myeloid leukemiacombination therapycytarabineING4oncolytic vaccinia virus

Identifiers

PMID30410347
PMCPMC6199215
OpenAlexW2897662838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.