ArticleClinical interventions in aging2018
Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study.
Article in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- A Community-Based Cross-Sectional Study to Assess the Prevalence of Polypharmacy and Potentially Inappropriate Medications among Elderly Patients in Urban Areas of Western Rajasthan.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Article
- Prevalence of polypharmacy and drug interactions in geriatric patients: A cross-sectional study from India.PloS one · 2026Article
- Polypharmacy and Potentially Inappropriate Medication in Iranian People With Metabolic Syndrome: Epidemiological Aspects and Related Factors, a Multi-Level Cross-Sectional National Study.Health science reports · 2025Article
- Examining determinants of control of metabolic syndrome among older adults with NCDs receiving service at NCD Plus clinics: multilevel analysis.BMC health services research · 2024Article
- Prescription Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Incidence of Depression Among Older Cancer Survivors With Osteoarthritis: A Machine Learning Analysis.Cancer informatics · 2023Article
- Determinants and consequences of polypharmacy in patients with a depressive disorder in later life.Acta psychiatrica Scandinavica · 2022Observational
- Comparison of the prevalence and nature of potentially inappropriate medication use in geriatric outpatients between tertiary and community healthcare settings: a multicenter cross-sectional study.International journal of clinical pharmacy · 2022Article
- Quality of life in patients with fibromyalgia: Contributions of disease symptoms, lifestyle and multi-medication.Frontiers in psychology · 2022Article
- Editorial: Chronic Pain and Health Disparities in Older Adults With Complex Needs.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Targeting neurotransmitter-mediated inflammatory mechanisms of psychiatric drugs to mitigate the double burden of multimorbidity and polypharmacy.Brain, behavior, & immunity - health · 2021Article
- Comparing Potential Drug-Drug Interactions in Companion Animal Medications Using Two Electronic Databases.Veterinary sciences · 2021Article
- High Prevalence of Multimorbidity and Polypharmacy in Elderly Patients With Chronic Pain Receiving Home Care are Associated With Multiple Medication-Related Problems.Frontiers in pharmacology · 2021Article
- Article
- Dopamine activates NF-κB and primes the NLRP3 inflammasome in primary human macrophages.Brain, behavior, & immunity - health · 2020Article
- An overview of prevalence, determinants and health outcomes of polypharmacy.Therapeutic advances in drug safety · 2020Review
- Dopaminergic impact of cART and anti-depressants on HIV neuropathogenesis in older adults.Brain research · 2019Review
- The silent epidemic of chronic pain in older adults.Progress in neuro-psychopharmacology & biological psychiatry · 2019Review
- A multicentric cross-sectional study to characterize the scale and impact of polypharmacy in rural Indian communities, conducted as part of health workers training.Journal of family medicine and primary care · 2019Article
- Comparison of potential drug-drug interactions with metabolic syndrome medications detected by two databases.PloS one · 2019Article
- Statistical concerns about the study: "Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study".Clinical interventions in aging · 2018Article
Corrections and comments
- Commented on by
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePolypharmacy (PP) is a clinical challenge in older adults. Therefore, assessment of daily drug consumption (DDC) and its relationships is important. First-line health services have a crucial role in monitoring and preventing PP. In this study, we aimed to assess DDC and investigate the risk factors for higher DDC among older adults in a primary care setting. PATIENTS AND
methodsA total of 1,000 patients aged ≥65 years who visited Melek Hatun Family Practice Center between December 1, 2014, and August 1, 2017, were enrolled in the study. All patients were seen either at the center or in their homes, and informed consent was obtained. Comprehensive geriatric assessment was performed for each subject. Data were analyzed using SPSS software (version 17). The daily number of medicines that each patient used (DDC) regardless of whether they were prescribed was the dependent variable. Relationships between DDC and other continuous variables were examined using Pearson's correlation. For between-group comparisons of DDC, Student's
resultsUnivariate tests showed relationships between DDC and various demographic and clinical parameters. The variables that remained significant at the last step of a stepwise linear regression analysis were metabolic syndrome, chronic pain, incontinence, increased serum creatinine level, increased Geriatric Depression Scale scores, reported gastric disturbances, and neutrophil/lymphocyte ratio.
conclusionAlong with certain chronic conditions, depressive symptoms and an inflammatory marker (neutrophil/lymphocyte ratio) were significantly and independently related to higher DDC. Longitudinal and larger studies are needed to further explore the multifaceted relationships of PP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.