Evidence map›Paper›PMID 30410205›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2017

Towards Closed-Loop Neuromodulation: A Wireless Miniaturized Neural Implant SoC.

Wentai Liu, Po-Min Wang, Yi-Kai Lo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wentai LiuUniversity of California, Los Angeles, Los Angeles, CA, USA 90095.
Po-Min WangUniversity of California, Los Angeles, Los Angeles, CA, USA 90095.
Yi-Kai LoUniversity of California, Los Angeles, Los Angeles, CA, USA 90095.

Funding

Spinal Epidural Electrode Array to Facilitate Standing and Stepping After SCIR01EB007615 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EDGERTON, REGGIE · 2008 to 2013
$4.9M
Spinal Epidural Electrode Array To Facilitate Standing and Stepping After SCIU01EB007615 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EDGERTON, REGGIE, GAD, PARAG · 2014 to 2018
$4.8M
NIBIB NIH HHS R01 EB007615NIBIB NIH HHS U01 EB007615
6 · The paper itself

Abstract

This work reports a platform technology toward the development of closed-loop neuromodulation. A neural implant based on the SoC developed in our laboratory is used as an example to illustrate the necessary functionalities for the efficacious implantable system. We also present an example of using the system to investigate the epidural stimulation for partial motor function recovery after spinal cord injury in a rat model. This hardware-software co-design tool demonstrate its promising potential towards an effective closed-loop neuromodulation for various biomedical applications.

Indexed as

bioelectronicsclosed-loopimplantNeuromodulationneuroprostheticsrecordingstimulationsystem-on-a-chip (SoC)

Identifiers

PMID30410205
PMCPMC6219869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.