Evidence map›Paper›PMID 30410191›Full record

ArticleJournal of physics D: Applied physics2018

Direct AFM Visualization of the Nanoscale Dynamics of Biomolecular Complexes.

Yuri L Lyubchenko

Abstract read
In one paragraph

Article in Journal of physics D: Applied physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Nanoscale Interaction of Endonuclease APE1 with DNA.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Restriction of RecG translocation by DNA mispairing.Biochimica et biophysica acta. General subjects · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yuri L LyubchenkoDepartment of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Funding

Mechanistic studies of stalled DNA replication fork rescueR01GM100156 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BIANCO, PIERO R, LYUBCHENKO, YURI L · 2013 to 2021
$4.0M
Protein Self-Assembly into NanoaggregatesR01GM096039 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LYUBCHENKO, YURI L · 2011 to 2018
$2.9M
APOBEC3-Nucleic Acid Interactions and Molecular Mechanisms of HIV RestrictionR01GM118006 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LYUBCHENKO, YURI L · 2016 to 2019
$1.5M
The Dimer Specific Anti-Amyloid-β Vaccine Based on the Nanoarray AssemblyR21NS101504 · NINDS · INSTITUTE FOR MOLECULAR MEDICINE · PI GHOCHIKYAN, ANAHIT · 2017 to 2018
$479k
NIGMS NIH HHS R01 GM096039NIGMS NIH HHS R01 GM100156NIGMS NIH HHS R01 GM118006NINDS NIH HHS R21 NS101504
6 · The paper itself

Abstract

High-speed AFM (HS-AFM) is an advanced technique with numerous applications in biology, particularly in molecular biophysics. Developed as a time-lapse AFM technique for direct imaging fully hydrated biological molecules, HS-AFM is currently capable of visualizing the dynamics of biological molecules and their complexes at a video-data acquisition rate. Spatial resolution at the nanometer level is another important characteristic of HS-AFM. This review focuses on examples of primarily protein-DNA complexes to illustrate the high temporal and spatial resolution capabilities of HS-AFM that have resulted in novel models and/or the functional mechanisms of these biological systems.

Identifiers

PMID30410191
PMCPMC6217977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.